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ENZYME entry: EC 3.1.1.55

Accepted Name
Acetylsalicylate deacetylase.
Alternative Name(s)
Aspirin esterase.
Reaction catalysed
Acetylsalicylate + H(2)O <=> salicylate + acetate
Comment(s)
  • Not identical with EC 3.1.1.1, EC 3.1.1.2, EC 3.1.1.7 or EC 3.1.1.8.
  • The activity of the liver cytosol enzyme is highest with acetyl esters of aryl alcohols, and thioesters are also hydrolyzed.
  • The microsomal enzyme also hydrolyzes some other negatively charged esters.
  • Best substrates were esters of salicylate with long-chain alcohols.
Cross-references
BRENDA3.1.1.55
EC2PDB3.1.1.55
ExplorEnz3.1.1.55
PRIAM enzyme-specific profiles3.1.1.55
KEGG Ligand Database for Enzyme Nomenclature3.1.1.55
IUBMB Enzyme Nomenclature3.1.1.55
IntEnz3.1.1.55
MEDLINEFind literature relating to 3.1.1.55
MetaCyc3.1.1.55

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.1.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.1.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.-.-.-