ENZYME entry: EC 3.1.1.59

Accepted Name
Juvenile-hormone esterase.
Alternative Name(s)
JH esterase.
Methyl-(2E,6E)-(10R,11S)-10,11-epoxy-3,7,11-trimethyltrideca-2,6-dienoate acylhydrolase.
Reaction catalysed
  • Juvenile hormone I + H(2)O <=> juvenile hormone I acid + methanol
  • Juvenile hormone III + H(2)O <=> juvenile hormone III acid + methanol
Comment(s)
Demethylates the insect juvenile hormones, JH1 and JH3, but does not hydrolyze the analogous ethyl or isopropyl esters.
Cross-references
PROSITEPDOC00112
BRENDA3.1.1.59
EC2PDB3.1.1.59
ExplorEnz3.1.1.59
PRIAM enzyme-specific profiles3.1.1.59
KEGG Ligand Database for Enzyme Nomenclature3.1.1.59
IUBMB Enzyme Nomenclature3.1.1.59
IntEnz3.1.1.59
MEDLINEFind literature relating to 3.1.1.59
MetaCyc3.1.1.59
UniProtKB/Swiss-Prot
P12992, ESTJ_HELVI;  P19985, ESTJ_MANSE;  P30809, JHEA_TRINI;  
P30810, JHEB_TRINI;  

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.1.1.-
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