ENZYME

ENZYME entry: EC 3.1.1.82

Accepted Name

Pheophorbidase.

Alternative Name(s)

Phedase.

PPD.

Reaction catalysed

Pheophorbide a + H(2)O <=> pyropheophorbide a + methanol + CO(2)

Comment(s)

Forms part of the chlorophyll degradation pathway, and is found in higher plants and in algae.
In higher plants it participates in de-greening processes such as fruit ripening, leaf senescence, and flowering.
Exists in two forms: type 1 is induced by senescence whereas type 2 is constitutively expressed.
Highly specific for pheophorbide as substrate (with a preference for pheophorbide a over pheophorbide b) as other chlorophyll derivatives such as protochlorophyllide a, pheophytin a and c, chlorophyll a and b, and chlorophyllide a cannot act as substrates.
Another enzyme, called pheophorbide demethoxycarbonylase (PDC), produces pyropheophorbide a from pheophorbide a without forming an intermediate although the precise reaction is not yet known.

Cross-references

PROSITE

BRENDA

EC2PDB

ExplorEnz

PRIAM enzyme-specific profiles

KEGG Ligand Database for Enzyme Nomenclature