ID   3.1.1.88
DE   pyrethroid hydrolase.
AN   permethrinase.
AN   pyrethroid-cleaving enzyme.
AN   pyrethroid-hydrolyzing carboxylesterase.
AN   pyrethroid-hydrolyzing esterase.
AN   pyrethroid-selective esterase.
CA   (-)-trans-permethrin + H2O = (1S,3R)-3-(2,2-dichlorovinyl)-2,2-
CA   dimethylcyclopropanecarboxylate + (3-phenoxyphenyl)methanol + H(+).
CC   -!- The enzyme is involved in degradation of pyrethroid pesticides.
CC   -!- The enzymes from Sphingobium sp., Klebsiella sp. and Aspergillus
CC       niger hydrolyze cis-permethrin at approximately equal rate to trans-
CC       permethrin.
CC   -!- The enzyme from mouse hydrolyzes trans-permethrin at a rate about
CC       22-fold higher than cis-permethrin.
DR   Q8QZR3, EST2A_MOUSE;  Q8K3R0, EST2A_RAT  ;  Q8BK48, EST2E_MOUSE;
DR   G3V7J5, EST2E_RAT  ;  Q52NW7, PYRHY_KLESP;  C0LA90, PYRHY_SPHWJ;
//