ENZYME entry: EC 3.1.11.1

Accepted Name
Exodeoxyribonuclease I.
Alternative Name(s)
E.coli exonuclease I.
Exonuclease I.
Reaction catalysed
Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates
Comment(s)
  • Preference for single-stranded DNA.
  • The Escherichia coli enzyme hydrolyzes glucosylated DNA.
  • Similar enzymes; mammalian DNase III, exonuclease IV, T2- and T4-induced exodeoxyribonucleases.
  • Formerly EC 3.1.4.25.
Cross-references
BRENDA3.1.11.1
EC2PDB3.1.11.1
ExplorEnz3.1.11.1
PRIAM enzyme-specific profiles3.1.11.1
KEGG Ligand Database for Enzyme Nomenclature3.1.11.1
IUBMB Enzyme Nomenclature3.1.11.1
IntEnz3.1.11.1
MEDLINEFind literature relating to 3.1.11.1
MetaCyc3.1.11.1
UniProtKB/Swiss-Prot
P57620, EX1_BUCAI;  Q8K923, EX1_BUCAP;  Q89A43, EX1_BUCBP;  
P04995, EX1_ECOLI;  P45188, EX1_HAEIN;  P04536, EXOD_BPT4;  

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