ENZYME entry: EC 3.1.2.15

Accepted Name
Ubiquitin thiolesterase.
Alternative Name(s)
Ubiquitin carboxy-terminal esterase.
Ubiquitin carboxy-terminal hydrolase.
Ubiquitin thioesterase.
Reaction catalysed
Ubiquitin C-terminal thioester + H(2)O <=> ubiquitin + a thiol
Comment(s)
  • Acts on esters formed between thiols such as dithiothreitol or glutathione and the C-terminal glycine residue of the polypeptide ubiquitin.
  • Also acts on AMP-ubiquitin.
Cross-references
PROSITEPDOC00127 ; PDOC00750
BRENDA3.1.2.15
EC2PDB3.1.2.15
ExplorEnz3.1.2.15
PRIAM enzyme-specific profiles3.1.2.15
KEGG Ligand Database for Enzyme Nomenclature3.1.2.15
IUBMB Enzyme Nomenclature3.1.2.15
IntEnz3.1.2.15
MEDLINEFind literature relating to 3.1.2.15
MetaCyc3.1.2.15

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