ENZYME entry: EC 3.1.2.22

Accepted Name
Palmitoyl-protein hydrolase.
Alternative Name(s)
Palmitoyl-protein thioesterase.
Reaction catalysed
Palmitoyl-[protein] + H(2)O <=> palmitate + [protein]
Comment(s)
  • Specific for long-chain thioesters of fatty acids.
  • Hydrolyzes fatty acids from S-acylated cysteine residues in proteins, palmitoyl cysteine and palmitoyl-CoA.
Cross-references
BRENDA3.1.2.22
EC2PDB3.1.2.22
ExplorEnz3.1.2.22
PRIAM enzyme-specific profiles3.1.2.22
KEGG Ligand Database for Enzyme Nomenclature3.1.2.22
IUBMB Enzyme Nomenclature3.1.2.22
IntEnz3.1.2.22
MEDLINEFind literature relating to 3.1.2.22
MetaCyc3.1.2.22
UniProtKB/Swiss-Prot
O59747, PDF1_SCHPO;  P45478, PPT1_BOVIN;  Q20390, PPT1_CAEEL;  
Q9W3C7, PPT1_DROME;  P50897, PPT1_HUMAN;  Q8HXW6, PPT1_MACFA;  
O88531, PPT1_MOUSE;  P45479, PPT1_RAT;  Q54CM0, PPT3_DICDI;  

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.1.2.-
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