ENZYME entry: EC 3.1.2.27
| Accepted Name |
|---|
| Choloyl-CoA hydrolase.
|
| Alternative Name(s) |
|---|
| Chenodeoxycholoyl-coenzyme A thioesterase. |
| Choloyl-coenzyme A thioesterase. |
| Peroxisomal acyl-CoA thioesterase 2. |
| PTE-2. |
| Reaction catalysed |
|---|
| Choloyl-CoA + H(2)O <=> cholate + CoA |
| Comment(s) |
|---|
- Also acts on chenodeoxycholoyl-CoA and to a lesser extent on short-
and medium- to long-chain acyl-CoA's, and other substrates, including
trihydroxycoprostanoyl-CoA, hydroxymethylglutaryl-CoA and branched
chain acyl-CoA's, all of which are present in peroxisomes.
- The enzyme is strongly inhibited by CoA and may be involved in
controlling CoA levels in the peroxisome.
|
| Cross-references |
|---|
| BRENDA | 3.1.2.27 |
| EC2PDB | 3.1.2.27 |
| ExplorEnz | 3.1.2.27 |
| PRIAM enzyme-specific profiles | 3.1.2.27 |
| KEGG Ligand Database for Enzyme Nomenclature | 3.1.2.27 |
| IUBMB Enzyme Nomenclature | 3.1.2.27 |
| IntEnz | 3.1.2.27 |
| MEDLINE | Find literature relating to 3.1.2.27 |
| MetaCyc | 3.1.2.27 |
| UniProtKB/Swiss-Prot |
|
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