ID 3.1.2.27 DE Choloyl-CoA hydrolase. AN Chenodeoxycholoyl-coenzyme A thioesterase. AN Choloyl-coenzyme A thioesterase. AN Peroxisomal acyl-CoA thioesterase 2. AN PTE-2. CA Choloyl-CoA + H(2)O = cholate + CoA. CC -!- Also acts on chenodeoxycholoyl-CoA and to a lesser extent on short- CC and medium- to long-chain acyl-CoA's, and other substrates, including CC trihydroxycoprostanoyl-CoA, hydroxymethylglutaryl-CoA and branched CC chain acyl-CoA's, all of which are present in peroxisomes. CC -!- The enzyme is strongly inhibited by CoA and may be involved in CC controlling CoA levels in the peroxisome. DR O14734, ACOT8_HUMAN; P58137, ACOT8_MOUSE; Q8VHK0, ACOT8_RAT ; //