Due to scheduled maintenance work, this service may not be available on Monday January 22nd between 08.00 am and 9.00 am CEST
To improve security and privacy, we are moving our web pages and services from HTTP to HTTPS.
To give users of web services time to transition to HTTPS, we will support separate HTTP and HTTPS services until the end of 2017.
From January 2018 most HTTP traffic will be automatically redirected to HTTPS. [more...] View this page in https
ENZYME entry: EC 220.127.116.11
View entry in original ENZYME format
View entry in raw text format (no links)
in this entry
|Fluoroacetyl-CoA + H(2)O <=> fluoroacetate + CoA|
- Fluoroacetate is extremely toxic.
- It reacts with CoA to form fluoroacetyl-CoA, which substitutes for
acetyl CoA and reacts with EC 18.104.22.168 to produce fluorocitrate,
a metabolite of which binds very tightly to EC 22.214.171.124 and halts the
- This enzyme hydrolyzes fluoroacetyl-CoA before it can react with
citrate synthase, and thus confers fluoroacetate resistance on the
organisms that produce it.
- It has been described in the poisonous plant Dichapetalum cymosum and
the bacterium Streptomyces cattleya, both of which are fluoroacetate
|PRIAM enzyme-specific profiles||126.96.36.199|
|KEGG Ligand Database for Enzyme Nomenclature||188.8.131.52|
|IUBMB Enzyme Nomenclature||184.108.40.206|
|MEDLINE||Find literature relating to 220.127.116.11|
, with possibility to download in different formats, align etc.
entries corresponding to 3.1.2.-
entries corresponding to 3.1.-.-
entries corresponding to 3.-.-.-