ENZYME entry: EC 3.1.21.1
| Accepted Name |
|---|
| Deoxyribonuclease I.
|
| Alternative Name(s) |
|---|
| DNase. |
| Pancreatic DNase. |
| Thymonuclease. |
| Reaction catalysed |
|---|
| Endonucleolytic cleavage to 5'-phosphodinucleotide and 5'-phosphooligonucleotide end-products |
| Comment(s) |
|---|
- Preference for double-stranded DNA.
- Similar enzymes: streptococcal DNase (streptodornase),
T4 endonuclease II, T7 endonuclease II, Escherichia coli endonuclease
I, 'nicking' nuclease of calf thymus, colicin E2 and E3.
- Formerly EC 3.1.4.5.
|
| Cross-references |
|---|
| PROSITE | PDOC00711 |
| BRENDA | 3.1.21.1 |
| EC2PDB | 3.1.21.1 |
| ExplorEnz | 3.1.21.1 |
| PRIAM enzyme-specific profiles | 3.1.21.1 |
| KEGG Ligand Database for Enzyme Nomenclature | 3.1.21.1 |
| IUBMB Enzyme Nomenclature | 3.1.21.1 |
| IntEnz | 3.1.21.1 |
| MEDLINE | Find literature relating to 3.1.21.1 |
| MetaCyc | 3.1.21.1 |
| UniProtKB/Swiss-Prot |
| P00639, DNAS1_BOVIN; | Q767J3, DNAS1_CANFA; | Q9YGI5, DNAS1_CHICK; |
| Q4AEE3, DNAS1_HORSE; | P24855, DNAS1_HUMAN; | P49183, DNAS1_MOUSE; |
| O42446, DNAS1_OREMO; | P11936, DNAS1_PIG; | O18998, DNAS1_RABIT; |
| P21704, DNAS1_RAT; | P11937, DNAS1_SHEEP; | P26295, DRN1_STREQ; |
| P57487, END1_BUCAI; | Q89AD7, END1_BUCBP; | P25736, END1_ECOLI; |
| P07059, END2_BPT4; |
|
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