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ENZYME entry: EC 220.127.116.11
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|Type I site-specific deoxyribonuclease.
|Type I restriction enzyme.|
|Endonucleolytic cleavage of DNA to give random double-stranded fragments with terminal 5'-phosphates; ATP is simultaneously hydrolyzed|
- Large group of enzymes that have an absolute requirement for ATP (or
dATP) and S-adenosyl-L-methionine.
- They recognize specific short DNA sequences and cleave at sites
remote from the recognition sequence.
- Multifunctional proteins which also catalyze the reactions of
EC 18.104.22.168 and EC 22.214.171.124, with similar site specificity.
- Formerly EC 126.96.36.199 and EC 188.8.131.52.
- See the REBASE database for a complete list of these enzymes:
|PRIAM enzyme-specific profiles||184.108.40.206|
|KEGG Ligand Database for Enzyme Nomenclature||220.127.116.11|
|IUBMB Enzyme Nomenclature||18.104.22.168|
|MEDLINE||Find literature relating to 22.214.171.124|
|Q5HJH8, HSDR_STAAC; ||Q99X26, HSDR_STAAM; ||Q7A801, HSDR_STAAN; |
|Q6GKB1, HSDR_STAAR; ||Q6GCT1, HSDR_STAAS; ||Q8NYL9, HSDR_STAAW; |
|Q5HK76, HSDR_STAEQ; ||Q4A127, HSDR_STAS1; ||P10486, T1R1_ECOLX; |
|Q07736, T1RA_ECOLX; ||Q47281, T1RE_ECOLX; ||O05052, T1RH_HAEIN; |
|Q60295, T1RH_METJA; ||P08956, T1RK_ECOLI; ||P17224, T1RP_ECOLX; |
|P75431, T1RX_MYCPN; ||P75433, T1RY_MYCPN; |
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