ID   3.1.21.3
DE   type I site-specific deoxyribonuclease.
AN   type I restriction enzyme.
CA   Endonucleolytic cleavage of DNA to give random double-stranded fragments
CA   with terminal 5'-phosphates, ATP is simultaneously hydrolyzed.
CC   -!- Large group of enzymes that have an absolute requirement for ATP (or
CC       dATP) and S-adenosyl-L-methionine.
CC   -!- They recognize specific short DNA sequences and cleave at sites
CC       remote from the recognition sequence.
CC   -!- Multifunctional proteins which also catalyze the reactions of
CC       EC 2.1.1.72 and EC 2.1.1.73, with similar site specificity.
CC   -!- See the REBASE database for a complete list of these enzymes:
CC       http://rebase.neb.com/rebase/
CC   -!- Formerly EC 3.1.24.1 and EC 3.1.24.2.
DR   Q5HJH8, HSDR_STAAC ;  Q99X26, HSDR_STAAM ;  Q7A801, HSDR_STAAN ;
DR   Q6GKB1, HSDR_STAAR ;  Q6GCT1, HSDR_STAAS ;  Q8NYL9, HSDR_STAAW ;
DR   Q5HK76, HSDR_STAEQ ;  Q4A127, HSDR_STAS1 ;  P10486, T1R1_ECOLX ;
DR   Q57588, T1R1_METJA ;  Q58611, T1R2_METJA ;  Q07736, T1RA_ECOLX ;
DR   Q47281, T1RE_ECOLX ;  O05052, T1RH_HAEIN ;  Q60295, T1RH_METJA ;
DR   P08956, T1RK_ECOLI ;  P17224, T1RP_ECOLX ;
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