ENZYME entry: EC 3.1.21.6

Accepted Name
CC-preferring endodeoxyribonuclease.
Alternative Name(s)
5'-CC-3'-preferring endodeoxyribonuclease.
Streptomyces glaucescens exocytoplasmic endodeoxyribonuclease.
Streptomyces glaucescens exocytoplasmic endonuclease.
Reaction catalysed
Endonucleolytic cleavage to give 5'-phosphooligonucleotide end-products, with a preference for cleavage within the sequence CC
Cofactor(s)
Mg(2+).
Comment(s)
  • Prefers CC sites in double-stranded circular and linear DNA.
  • Greater affinity for double-stranded than single-stranded DNA.
  • Produces nicks, generating double-stranded fragments with 5'- and/or 3'-protruding single-stranded tails.
Cross-references
BRENDA3.1.21.6
EC2PDB3.1.21.6
ExplorEnz3.1.21.6
PRIAM enzyme-specific profiles3.1.21.6
KEGG Ligand Database for Enzyme Nomenclature3.1.21.6
IUBMB Enzyme Nomenclature3.1.21.6
IntEnz3.1.21.6
MEDLINEFind literature relating to 3.1.21.6
MetaCyc3.1.21.6

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.1.21.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.1.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.-.-.-