ENZYME entry: EC 3.1.26.n2

Accepted Name
Argonaute-2.
Alternative Name(s)
Argonaute RISC catalytic component 2.
Eukaryotic translation initiation factor 2C 2.
Reaction catalysed
Endonucleolytic cleavage to 5'-phosphomonoester
Comment(s)
The enzyme, isolated from animals, is required for RNA-mediated gene silencing (RNAi).
Cross-references
UniProtKB/Swiss-Prot
Q6QME8, AGO2_BOVIN;  Q9UKV8, AGO2_HUMAN;  Q8CJG0, AGO2_MOUSE;  
O77503, AGO2_RABIT;  Q9QZ81, AGO2_RAT;  Q6DCX2, AGO2_XENLA;  
Q6DJB9, AGO2_XENTR;  

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