ENZYME entry: EC 3.1.3.64

Accepted Name
Phosphatidylinositol-3-phosphatase.
Alternative Name(s)
D-myo-inositol-1,3-bisphosphate 3-phosphohydrolase.
Inositol 1,3-bisphosphate phosphatase.
Inositol-1,3-bisphosphate 3-phosphatase.
Inositol-polyphosphate 3-phosphatase.
Phosphatidyl-3-phosphate 3-phosphohydrolase.
Reaction catalysed
1-phosphatidyl-1D-myo-inositol 3-phosphate + H(2)O <=> 1-phosphatidyl-1D-myo-inositol + phosphate
Comment(s)
  • This enzyme still works when the 2,3-bis(acyloxy)propyl group is removed, i.e., it hydrolyzes Ins(1,3)P(2) to Ins-1-P.
  • Formerly EC 3.1.3.65.
Cross-references
BRENDA3.1.3.64
EC2PDB3.1.3.64
ExplorEnz3.1.3.64
PRIAM enzyme-specific profiles3.1.3.64
KEGG Ligand Database for Enzyme Nomenclature3.1.3.64
IUBMB Enzyme Nomenclature3.1.3.64
IntEnz3.1.3.64
MEDLINEFind literature relating to 3.1.3.64
MetaCyc3.1.3.64
UniProtKB/Swiss-Prot
A6QLT4, MTM1_BOVIN;  Q13496, MTM1_HUMAN;  Q9Z2C5, MTM1_MOUSE;  
Q5R9S3, MTM1_PONAB;  Q6AXQ4, MTM1_RAT;  Q52KU6, MTM1_XENLA;  
Q5EB32, MTM1_XENTR;  Q13613, MTMR1_HUMAN;  Q9Z2C4, MTMR1_MOUSE;  
A6QLT2, MTMR2_BOVIN;  Q5ZIV1, MTMR2_CHICK;  A0JMK5, MTMR2_DANRE;  
Q13614, MTMR2_HUMAN;  Q9Z2D1, MTMR2_MOUSE;  Q5REB9, MTMR2_PONAB;  
Q22712, MTMR3_CAEEL;  Q13615, MTMR3_HUMAN;  Q8K296, MTMR3_MOUSE;  
Q5PQT2, MTMR3_RAT;  F4J3T8, MYTM1_ARATH;  F4JWB3, MYTM2_ARATH;  
O13819, YMR1_SCHPO;  P47147, YMR1_YEAST;  

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