ID   3.1.3.67
DE   phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase.
AN   phosphatidylinositol-3,4,5-trisphosphate 3-phosphohydrolase.
CA   a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) +
CA   H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-
CA   bisphosphate) + phosphate.
CC   -!- Does not dephosphorylate inositol 4,5-bisphosphate.
CC   -!- This enzyme still works when the 2,3-bis(acyloxy)propyl group is
CC       removed, i.e., it hydrolyzes Ins(1,3,4,5)P4 to Ins(1,4,5)P3.
DR   Q54JL7, CNRN_DICDI ;  Q9FLZ5, PTEN1_ARATH;  G5EE01, PTEN_CAEEL ;
DR   P60483, PTEN_CANLF ;  Q8T9S7, PTEN_DICDI ;  P60484, PTEN_HUMAN ;
DR   O08586, PTEN_MOUSE ;  O54857, PTEN_RAT   ;  O94526, PTEN_SCHPO ;
DR   Q9PUT6, PTEN_XENLA ;  Q9LT75, PTN2A_ARATH;  Q8H106, PTN2B_ARATH;
DR   P53916, TEP1_YEAST ;  Q6XPS3, TPTE2_HUMAN;  Q4R6N0, TPTE2_MACFA;
//