ENZYME entry: EC 3.1.4.17

Accepted Name
3',5'-cyclic-nucleotide phosphodiesterase.
Alternative Name(s)
Cyclic AMP phosphodiesterase.
Reaction catalysed
Nucleoside 3',5'-cyclic phosphate + H(2)O <=> nucleoside 5'-phosphate
Comment(s)
Acts on 3',5'-cyclic AMP, 3',5'-cyclic dAMP, 3',5'-cyclic IMP, 3',5'-cyclic GMP and 3',5'-cyclic CMP.
Cross-references
PROSITEPDOC00116 ; PDOC00530
BRENDA3.1.4.17
EC2PDB3.1.4.17
ExplorEnz3.1.4.17
PRIAM enzyme-specific profiles3.1.4.17
KEGG Ligand Database for Enzyme Nomenclature3.1.4.17
IUBMB Enzyme Nomenclature3.1.4.17
IntEnz3.1.4.17
MEDLINEFind literature relating to 3.1.4.17
MetaCyc3.1.4.17
UniProtKB/Swiss-Prot
O25683, CNPDE_HELPY;  D5V0N9, CPDA_ARCNC;  Q47WJ3, CPDA_COLP3;  
Q839Z9, CPDA_COXBU;  P0AEW5, CPDA_ECO57;  P0AEW4, CPDA_ECOLI;  
E3GCF1, CPDA_ENTLS;  C9RR52, CPDA_FIBSS;  P44685, CPDA_HAEIN;  
D5VAD8, CPDA_MORCR;  P9WP64, CPDA_MYCTO;  P9WP65, CPDA_MYCTU;  
Q8YLG0, CPDA_NOSS1;  D4P095, CPDA_PSEAI;  E6RHP9, CPDA_PSEU9;  
Q4FQ25, CPDA_PSYA2;  A5WBU9, CPDA_PSYWF;  C1A2D8, CPDA_RHOE4;  
Q6NDI4, CPDA_RHOPA;  A1AWV4, CPDA_RUTMC;  Q93GX3, CPDA_STRAW;  
P05675, CPDA_SYNP6;  A5GLK1, CPDA_SYNPW;  Q7U7W2, CPDA_SYNPX;  
A5CWE4, CPDA_VESOH;  Q8DEI1, CPDA_VIBVU;  D3UX49, CPDA_XENBS;  
Q56686, CPDP_ALIFS;  Q8ZD92, CPDP_YERPE;  Q9Y233, PDE10_HUMAN;  
Q8CA95, PDE10_MOUSE;  Q9QYJ6, PDE10_RAT;  Q9VJ79, PDE11_DROME;  
Q9HCR9, PDE11_HUMAN;  P0C1Q2, PDE11_MOUSE;  Q8VID6, PDE11_RAT;  
Q1KKS3, PDE11_TAKRU;  P14100, PDE1A_BOVIN;  P54750, PDE1A_HUMAN;  
Q61481, PDE1A_MOUSE;  Q01061, PDE1B_BOVIN;  Q64395, PDE1B_CRIGR;  
Q01064, PDE1B_HUMAN;  Q01065, PDE1B_MOUSE;  Q01066, PDE1B_RAT;  
Q14123, PDE1C_HUMAN;  Q64338, PDE1C_MOUSE;  Q63421, PDE1C_RAT;  
O18696, PDE1_CAEEL;  P32782, PDE1_CANAX;  P36599, PDE1_SCHPO;  
P22434, PDE1_YEAST;  P14099, PDE2A_BOVIN;  O00408, PDE2A_HUMAN;  
Q922S4, PDE2A_MOUSE;  Q01062, PDE2A_RAT;  P30645, PDE2_CAEEL;  
P06776, PDE2_YEAST;  Q14432, PDE3A_HUMAN;  Q9Z0X4, PDE3A_MOUSE;  
Q62865, PDE3A_RAT;  Q13370, PDE3B_HUMAN;  Q61409, PDE3B_MOUSE;  
Q63085, PDE3B_RAT;  Q8I0P7, PDE3_CAEEL;  Q22000, PDE4_CAEEL;  
P91119, PDE5_CAEEL;  Q9N2V9, PDE6_CAEEL;  

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