ID 3.1.4.53 DE 3',5'-cyclic-AMP phosphodiesterase. AN cAMP-specific PDE. AN cAMP-specific phosphodiesterase. CA Adenosine 3',5'-cyclic phosphate + H(2)O = adenosine 5'-phosphate. CC -!- Specific for 3',5'-cAMP and does not hydrolyze other nucleoside CC 3',5'-cyclic phosphates such as cGMP (cf. EC 3.1.4.17 and CC EC 3.1.4.35). CC -!- It is involved in modulation of the levels of cAMP, which is a CC mediator in the processes of cell transformation and proliferation. CC -!- Formerly EC 3.1.4.n1. PR PROSITE; PDOC00116; DR P12019, PDE1_DICDI ; Q23917, PDE2_DICDI ; Q86H13, PDE4_DICDI ; DR Q8MM62, PDE6_DICDI ; Q54HY0, PDE7_DICDI ; //