ENZYME entry: EC 3.1.8.1
| Accepted Name |
|---|
| Aryldialkylphosphatase.
|
| Alternative Name(s) |
|---|
| A-esterase. |
| Aryltriphosphatase. |
| Paraoxon hydrolase. |
| Paraoxonase. |
| Phosphotriesterase. |
| Reaction catalysed |
|---|
| An aryl dialkyl phosphate + H(2)O <=> dialkyl phosphate + an aryl alcohol |
| Cofactor(s) |
|---|
| Divalent cation.
|
| Comment(s) |
|---|
- Acts on organophosphorus compounds (such as paraoxon) including
esters of phosphonic and phosphinic acids.
- Inhibited by chelating agents.
- Previously regarded as identical with EC 3.1.1.2.
|
| Cross-references |
|---|
| PROSITE | PDOC01026 |
| BRENDA | 3.1.8.1 |
| EC2PDB | 3.1.8.1 |
| ExplorEnz | 3.1.8.1 |
| PRIAM enzyme-specific profiles | 3.1.8.1 |
| KEGG Ligand Database for Enzyme Nomenclature | 3.1.8.1 |
| IUBMB Enzyme Nomenclature | 3.1.8.1 |
| IntEnz | 3.1.8.1 |
| MEDLINE | Find literature relating to 3.1.8.1 |
| MetaCyc | 3.1.8.1 |
| UniProtKB/Swiss-Prot |
| P0A434, OPD_BREDI; | P0A433, OPD_FLAS2; | Q44238, PEPQ_ALTSX; |
| Q97VT7, PHP_SULSO; | P27169, PON1_HUMAN; | P52430, PON1_MOUSE; |
| P27170, PON1_RABIT; | P55159, PON1_RAT; | Q90952, PON2_CHICK; |
| Q91090, PON2_MELGA; | Q15166, PON3_HUMAN; | Q62087, PON3_MOUSE; |
| Q9BGN0, PON3_RABIT; | Q68FP2, PON3_RAT; |
|
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