ENZYME entry: EC 3.2.1.158

Accepted Name
Alpha-agarase.
Alternative Name(s)
Agarase A33.
Reaction catalysed
Endohydrolysis of 1,3-alpha-L-galactosidic linkages in agarose, yielding agarotetraose as the major product
Cofactor(s)
Ca(2+).
Comment(s)
  • The enzyme from Thalassomonas sp. can use agarose, agarohexaose and neoagarohexaose as substrate.
  • The products of agarohexaose hydrolysis are dimers and tetramers, with agarotetraose being the predominant product, whereas hydrolysis of neoagarohexaose gives rise to two types of trimer.
  • While the enzyme can also hydrolyze the highly sulfated agarose porphyran very efficiently, it cannot hydrolyze kappa-carrageenan and iota-carrageenan.
Cross-references
BRENDA3.2.1.158
EC2PDB3.2.1.158
ExplorEnz3.2.1.158
PRIAM enzyme-specific profiles3.2.1.158
KEGG Ligand Database for Enzyme Nomenclature3.2.1.158
IUBMB Enzyme Nomenclature3.2.1.158
IntEnz3.2.1.158
MEDLINEFind literature relating to 3.2.1.158
MetaCyc3.2.1.158
UniProtKB/Swiss-Prot
Q9LAP7, AAGAR_ALTAG;  A1IGV8, AAGAR_THASX;  

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.2.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.2.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.-.-.-