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ENZYME entry: EC 3.2.1.161

Accepted Name

beta-apiosyl-beta-glucosidase

Alternative Name(s)

furcatin hydrolase

isoflavonoid-7-O-beta[D-apiosyl-(1->6)-beta-D-glucoside] disaccharidase

isoflavonoid 7-O-beta-apiosyl-glucoside beta-glucosidase

Reaction catalysed

7-[beta-D-apiofuranosyl-(1->6)-beta-D-glucopyranosyloxy]isoflavonoid + H2O = a 7-hydroxyisoflavonoid + beta-D-apiofuranosyl-(1->6)-D-glucose

Comment(s)

Removes disaccharides from the natural substrates dalpatein 7-O-beta- D-apiofuranosyl-(1->6)-beta-D-glucopyranoside and 7-hydroxy- 2',4',5',6-tetramethoxy-7-O-beta-D-apiofuranosyl-(1->6)-beta-D- glucopyranoside (dalnigrein 7-O-beta-D-apiofuranosyl-(1->6)-beta-D- glucopyranoside) although it can also remove a single glucose residue from isoflavonoid 7-O-glucosides.
Daidzin and genistin are also substrates.

Cross-references

BRENDA

EC2PDB

ExplorEnz

PRIAM enzyme-specific profiles

KEGG Ligand Database for Enzyme Nomenclature

IUBMB Enzyme Nomenclature

IntEnz

MEDLINE

MetaCyc

Rhea expert-curated reactions

UniProtKB/Swiss-Prot

A3RF67, BAGBG_DALNI

Q75W17, FURH_VIBFR

All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.

All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.2.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.2.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.-.-.-