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ENZYME entry: EC 3.2.1.179

Accepted Name
Gellan tetrasaccharide unsaturated glucuronyl hydrolase.
Alternative Name(s)
Unsaturated glucuronyl hydrolase.
Reaction catalysed
Beta-D-4-deoxy-Delta(4)-GlcAp-(1->4)-beta-D-Glcp-(1->4)-alpha-L-Rhap-(1->3)-beta-D-Glcp + H(2)O <=> 5-dehydro-4-deoxy-D-glucuronate + beta-D-Glcp-(1->4)-alpha-L-Rhap-(1->3)-beta-D-Glcp
Comment(s)
  • The enzyme releases 4-deoxy-4(5)-unsaturated D-glucuronic acid from oligosaccharides produced by polysaccharide lyases, e.g. the tetrasaccharide beta-D-4-deoxy-Delta(4)-GlcAp-(1->4)-beta-D-Glcp- (1->4)-alpha-L-Rhap-(1->3)-beta-D-Glcp produced by EC 4.2.2.25.
  • The enzyme can also hydrolyze unsaturated chondroitin and hyaluronate disaccharides (beta-D-4-deoxy-Delta(4)-GlcAp-(1->3)-beta-D-GalNAc, beta-D-4-deoxy-Delta(4)-GlcAp-(1->3)-beta-D-GalNAc6S, beta-D-4-deoxy- Delta(4)-GlcAp2S-(1->3)-beta-D-GalNAc, beta-D-4-deoxy-Delta(4)-GlcAp- (1->3)-beta-D-GlcNAc), preferring the unsulfated disaccharides to the sulfated disaccharides.
Cross-references
BRENDA3.2.1.179
EC2PDB3.2.1.179
ExplorEnz3.2.1.179
PRIAM enzyme-specific profiles3.2.1.179
KEGG Ligand Database for Enzyme Nomenclature3.2.1.179
IUBMB Enzyme Nomenclature3.2.1.179
IntEnz3.2.1.179
MEDLINEFind literature relating to 3.2.1.179
MetaCyc3.2.1.179
UniProtKB/Swiss-Prot
Q9RC92, UGL_BACGL

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All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.2.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.2.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.-.-.-