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ENZYME entry: EC

Accepted Name
Unsaturated chondroitin disaccharide hydrolase.
Alternative Name(s)
Unsaturated glucuronyl hydrolase.
Reaction catalysed
Beta-D-4-deoxy-Delta(4)-GlcAp-(1->3)-beta-D-GalNAc6S + H(2)O <=> 5-dehydro-4-deoxy-D-glucuronate + N-acetyl-beta-D-galactosamine-6-O-sulfate
  • The enzyme releases 4-deoxy-4,5-didehydro D-glucuronic acid or 4-deoxy-4,5-didehydro L-iduronic acid from chondroitin disaccharides, hyaluronan disaccharides and heparin disaccharides and cleaves both glycosidic (1->3) and (1->4) bonds.
  • It prefers the sulfated disaccharides to the unsulfated disaccharides.
PRIAM enzyme-specific profiles3.2.1.180
KEGG Ligand Database for Enzyme Nomenclature3.2.1.180
IUBMB Enzyme Nomenclature3.2.1.180
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