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ENZYME entry: EC 3.2.1.20

Accepted Name
Alpha-glucosidase.
Alternative Name(s)
Acid maltase.
Glucoinvertase.
Glucosidosucrase.
Lysosomal alpha-glucosidase.
Maltase.
Maltase-glucoamylase.
Reaction catalysed
Hydrolysis of terminal, non-reducing (1->4)-linked alpha-D-glucose residues with release of alpha-D-glucose
Comment(s)
  • Group of enzymes whose specificity is directed mainly toward the exohydrolysis of 1,4-alpha-glucosidic linkages, and that hydrolyze oligosaccharides rapidly, relative to polysaccharides, which are hydrolyzed relatively slowly, or not at all.
  • The intestinal enzyme also hydrolyzes polysaccharides, catalyzing the reactions of EC 3.2.1.3, and, more slowly, hydrolyzes 1,6-alpha-D- glucose links.
Cross-references
PROSITEPDOC00120 ; PDOC01027
BRENDA3.2.1.20
EC2PDB3.2.1.20
ExplorEnz3.2.1.20
PRIAM enzyme-specific profiles3.2.1.20
KEGG Ligand Database for Enzyme Nomenclature3.2.1.20
IUBMB Enzyme Nomenclature3.2.1.20
IntEnz3.2.1.20
MEDLINEFind literature relating to 3.2.1.20
MetaCyc3.2.1.20
UniProtKB/Swiss-Prot
A1CNK4, AGDC_ASPCL;  B0XNL6, AGDC_ASPFC;  B8MZ41, AGDC_ASPFN;  
Q4WRH9, AGDC_ASPFU;  Q2UQV7, AGDC_ASPOR;  Q0CMA7, AGDC_ASPTN;  
Q5AWI5, AGDC_EMENI;  A1D1E6, AGDC_NEOFI;  Q9F234, AGL2_BACTQ;  
Q9Z3R8, AGLA_RHIME;  O33830, AGLA_THEMA;  O86960, AGLA_THENE;  
P56526, AGLU_ASPNG;  Q12558, AGLU_ASPOR;  O04931, AGLU_BETVU;  
P29064, AGLU_CANTS;  Q43763, AGLU_HORVU;  Q92442, AGLU_MUCJA;  
Q653V7, AGLU_ORYSJ;  Q9C0Y4, AGLU_SCHPO;  O04893, AGLU_SPIOL;  
D0KQM8, AGLU_SULS9;  P0CD66, AGLU_SULSO;  O00906, AGLU_TETPY;  
P43473, AGL_PEDPE;  Q8TET4, GANC_HUMAN;  Q9MYM4, LYAG_BOVIN;  
P10253, LYAG_HUMAN;  P70699, LYAG_MOUSE;  Q5R7A9, LYAG_PONAB;  
Q6P7A9, LYAG_RAT;  P53341, MAL12_YEAST;  Q17058, MAL1_APIME;  
P07190, MAL1_DROME;  O16098, MAL1_DROVI;  P07191, MAL2_DROME;  
O16099, MAL2_DROVI;  P38158, MAL32_YEAST;  P07192, MAL3_DROME;  
P07265, MAL62_YEASX;  P13080, MALT_AEDAE;  P80072, MALT_BACTQ;  
Q02751, MALT_CANAX;  Q9P6J3, MALT_SCHPO;  P21517, MALZ_ECOLI;  
O43451, MGA_HUMAN;  Q9AI65, PALH_ERWRD;  P32138, YIHQ_ECOLI;  

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All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.2.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.2.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.-.-.-