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ENZYME entry: EC 3.2.1.28

Accepted Name
Alpha,alpha-trehalase.
Alternative Name(s)
Trehalase.
Reaction catalysed
Alpha,alpha-trehalose + H(2)O <=> beta-D-glucose + alpha-D-glucose
Comment(s)
  • The enzyme is an anomer-inverting glucosidase that catalyzes the hydrolysis of the alpha-glucosidic O-linkage of alpha,alpha- trehalose, releasing initially equimolar amounts of alpha- and beta- D-glucose.
  • It is widely distributed in microorganisms, plants, invertebrates and vertebrates.
Cross-references
PROSITEPDOC00717
BRENDA3.2.1.28
EC2PDB3.2.1.28
ExplorEnz3.2.1.28
PRIAM enzyme-specific profiles3.2.1.28
KEGG Ligand Database for Enzyme Nomenclature3.2.1.28
IUBMB Enzyme Nomenclature3.2.1.28
IntEnz3.2.1.28
MEDLINEFind literature relating to 3.2.1.28
MetaCyc3.2.1.28
UniProtKB/Swiss-Prot
Q5AAU5, ATC1_CANAL;  P48016, ATH1_YEAST;  Q9SU50, TRE1_ARATH;  
A8J4S9, TREA_APIME;  P32358, TREA_BOMMO;  P52494, TREA_CANAX;  
A8AFT6, TREA_CITK8;  Q54QZ5, TREA_DICDI;  Q9W2M2, TREA_DROME;  
A7ZKW9, TREA_ECO24;  B7UQ86, TREA_ECO27;  B7MK99, TREA_ECO45;  
B7LGV7, TREA_ECO55;  Q8XDH7, TREA_ECO57;  B7NUW3, TREA_ECO7I;  
B7LXB1, TREA_ECO8A;  C4ZTN8, TREA_ECOBW;  B1XAN8, TREA_ECODH;  
A7ZZD1, TREA_ECOHS;  A1AAC5, TREA_ECOK1;  Q0TIH3, TREA_ECOL5;  
Q8CW46, TREA_ECOL6;  B1IU96, TREA_ECOLC;  P13482, TREA_ECOLI;  
B7N408, TREA_ECOLU;  B6I9Q8, TREA_ECOSE;  B1LHA4, TREA_ECOSM;  
Q1RCP3, TREA_ECOUT;  P78617, TREA_EMENI;  O43280, TREA_HUMAN;  
P49381, TREA_KLULA;  Q9JLT2, TREA_MOUSE;  Q8MMG9, TREA_PIMHY;  
Q9I165, TREA_PSEAE;  P19813, TREA_RABIT;  Q8XT38, TREA_RALSO;  
B5F4F0, TREA_SALA4;  Q57NL6, TREA_SALCH;  B5FTN7, TREA_SALDC;  
B5R2X4, TREA_SALEP;  B5R904, TREA_SALG2;  B4SUI9, TREA_SALNS;  
Q5PI73, TREA_SALPA;  A9MVX4, TREA_SALPB;  C0Q337, TREA_SALPC;  
B5BI56, TREA_SALPK;  B4TXW7, TREA_SALSV;  P59765, TREA_SALTI;  
Q8ZP20, TREA_SALTY;  O42893, TREA_SCHPO;  Q32H09, TREA_SHIDS;  
Q0T5J8, TREA_SHIF8;  Q83RP6, TREA_SHIFL;  P32359, TREA_TENMO;  
Q8PPT1, TREA_XANAC;  Q4UZ12, TREA_XANC8;  B0RNH1, TREA_XANCB;  
Q8P519, TREA_XANCP;  Q2NYS3, TREA_XANOM;  P32356, TREA_YEAST;  
Q757L1, TREB_ASHGO;  O42777, TREB_EMENI;  O42622, TREB_MAGO7;  
O42783, TREB_NEUCR;  P35172, TREB_YEAST;  A7ZT60, TREF_ECO24;  
B7UL72, TREF_ECO27;  B7MEM1, TREF_ECO45;  B7L603, TREF_ECO55;  
P62602, TREF_ECO57;  B5YVG5, TREF_ECO5E;  B7NNF3, TREF_ECO7I;  
B7N1V9, TREF_ECO81;  B7M3D0, TREF_ECO8A;  C4ZW66, TREF_ECOBW;  
B1X7X4, TREF_ECODH;  A8A5X9, TREF_ECOHS;  A1AH61, TREF_ECOK1;  
Q0TBT4, TREF_ECOL5;  Q8FCI4, TREF_ECOL6;  B1J0B4, TREF_ECOLC;  
P62601, TREF_ECOLI;  B7NEG2, TREF_ECOLU;  B6I385, TREF_ECOSE;  
B1LJ63, TREF_ECOSM;  Q1R584, TREF_ECOUT;  B7LSZ0, TREF_ESCF3;  
B5F9H0, TREF_SALA4;  A9MLK7, TREF_SALAR;  Q57IL9, TREF_SALCH;  
B5FKM4, TREF_SALDC;  B5R404, TREF_SALEP;  B5RGS3, TREF_SALG2;  
B4T8D8, TREF_SALHS;  B4SWF1, TREF_SALNS;  C0Q162, TREF_SALPC;  
B4TZ02, TREF_SALSV;  Q8Z277, TREF_SALTI;  Q8ZLC8, TREF_SALTY;  
B2U4I7, TREF_SHIB3;  Q31VA6, TREF_SHIBS;  Q0SZB4, TREF_SHIF8;  
Q83PS8, TREF_SHIFL;  Q3YWJ3, TREF_SHISS;  A0R0W9, TREH_MYCS2;  
P71741, TREH_MYCTU;  Q9FWC1, TRE_ORYSJ;  

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