ENZYME entry: EC 3.2.1.28

Accepted Name
Alpha,alpha-trehalase.
Alternative Name(s)
Trehalase.
Reaction catalysed
Alpha,alpha-trehalose + H(2)O <=> beta-D-glucose + alpha-D-glucose
Comment(s)
  • The enzyme is an anomer-inverting glucosidase that catalyzes the hydrolysis of the alpha-glucosidic O-linkage of alpha,alpha- trehalose, releasing initially equimolar amounts of alpha- and beta- D-glucose.
  • It is widely distributed in microorganisms, plants, invertebrates and vertebrates.
Cross-references
PROSITEPDOC00717
BRENDA3.2.1.28
EC2PDB3.2.1.28
ExplorEnz3.2.1.28
PRIAM enzyme-specific profiles3.2.1.28
KEGG Ligand Database for Enzyme Nomenclature3.2.1.28
IUBMB Enzyme Nomenclature3.2.1.28
IntEnz3.2.1.28
MEDLINEFind literature relating to 3.2.1.28
MetaCyc3.2.1.28
UniProtKB/Swiss-Prot
D4B5H9, ATC1_ARTBC;  Q5AAU5, ATC1_CANAL;  P48016, ATH1_YEAST;  
Q9SU50, TRE1_ARATH;  A8J4S9, TREA_APIME;  P32358, TREA_BOMMO;  
P52494, TREA_CANAX;  A8AFT6, TREA_CITK8;  Q54QZ5, TREA_DICDI;  
Q9W2M2, TREA_DROME;  A7ZKW9, TREA_ECO24;  B7UQ86, TREA_ECO27;  
B7MK99, TREA_ECO45;  B7LGV7, TREA_ECO55;  Q8XDH7, TREA_ECO57;  
B7NUW3, TREA_ECO7I;  B7LXB1, TREA_ECO8A;  C4ZTN8, TREA_ECOBW;  
B1XAN8, TREA_ECODH;  A7ZZD1, TREA_ECOHS;  A1AAC5, TREA_ECOK1;  
Q0TIH3, TREA_ECOL5;  Q8CW46, TREA_ECOL6;  B1IU96, TREA_ECOLC;  
P13482, TREA_ECOLI;  B7N408, TREA_ECOLU;  B6I9Q8, TREA_ECOSE;  
B1LHA4, TREA_ECOSM;  Q1RCP3, TREA_ECOUT;  P78617, TREA_EMENI;  
O43280, TREA_HUMAN;  P49381, TREA_KLULA;  Q9JLT2, TREA_MOUSE;  
Q8MMG9, TREA_PIMHY;  Q9I165, TREA_PSEAE;  P19813, TREA_RABIT;  
Q8XT38, TREA_RALSO;  B5F4F0, TREA_SALA4;  Q57NL6, TREA_SALCH;  
B5FTN7, TREA_SALDC;  B5R2X4, TREA_SALEP;  B5R904, TREA_SALG2;  
B4SUI9, TREA_SALNS;  Q5PI73, TREA_SALPA;  A9MVX4, TREA_SALPB;  
C0Q337, TREA_SALPC;  B5BI56, TREA_SALPK;  B4TXW7, TREA_SALSV;  
P59765, TREA_SALTI;  Q8ZP20, TREA_SALTY;  O42893, TREA_SCHPO;  
Q32H09, TREA_SHIDS;  Q0T5J8, TREA_SHIF8;  Q83RP6, TREA_SHIFL;  
P32359, TREA_TENMO;  Q8PPT1, TREA_XANAC;  Q4UZ12, TREA_XANC8;  
B0RNH1, TREA_XANCB;  Q8P519, TREA_XANCP;  Q2NYS3, TREA_XANOM;  
P32356, TREA_YEAST;  Q757L1, TREB_ASHGO;  O42777, TREB_EMENI;  
O42622, TREB_MAGO7;  O42783, TREB_NEUCR;  P35172, TREB_YEAST;  
A7ZT60, TREF_ECO24;  B7UL72, TREF_ECO27;  B7MEM1, TREF_ECO45;  
B7L603, TREF_ECO55;  P62602, TREF_ECO57;  B5YVG5, TREF_ECO5E;  
B7NNF3, TREF_ECO7I;  B7N1V9, TREF_ECO81;  B7M3D0, TREF_ECO8A;  
C4ZW66, TREF_ECOBW;  B1X7X4, TREF_ECODH;  A8A5X9, TREF_ECOHS;  
A1AH61, TREF_ECOK1;  Q0TBT4, TREF_ECOL5;  Q8FCI4, TREF_ECOL6;  
B1J0B4, TREF_ECOLC;  P62601, TREF_ECOLI;  B7NEG2, TREF_ECOLU;  
B6I385, TREF_ECOSE;  B1LJ63, TREF_ECOSM;  Q1R584, TREF_ECOUT;  
B7LSZ0, TREF_ESCF3;  B5F9H0, TREF_SALA4;  A9MLK7, TREF_SALAR;  
Q57IL9, TREF_SALCH;  B5FKM4, TREF_SALDC;  B5R404, TREF_SALEP;  
B5RGS3, TREF_SALG2;  B4T8D8, TREF_SALHS;  B4SWF1, TREF_SALNS;  
C0Q162, TREF_SALPC;  B4TZ02, TREF_SALSV;  Q8Z277, TREF_SALTI;  
Q8ZLC8, TREF_SALTY;  B2U4I7, TREF_SHIB3;  Q31VA6, TREF_SHIBS;  
Q0SZB4, TREF_SHIF8;  Q83PS8, TREF_SHIFL;  Q3YWJ3, TREF_SHISS;  
A0R0W9, TREH_MYCS2;  P71741, TREH_MYCTU;  Q9FWC1, TRE_ORYSJ;  

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