To improve security and privacy, we are moving our web pages and services from HTTP to HTTPS.
To give users of web services time to transition to HTTPS, we will support separate HTTP and HTTPS services until the end of 2017.
From January 2018 most HTTP traffic will be automatically redirected to HTTPS. [more...]
View this page in https

ENZYME entry: EC 3.3.1.1

Accepted Name
Adenosylhomocysteinase.
Alternative Name(s)
Adenosylhomocysteine hydrolase.
AdoHcyase.
S-adenosylhomocysteinase.
S-adenosylhomocysteine hydrolase.
S-adenosylhomocysteine synthase.
SAHase.
Reaction catalysed
S-adenosyl-L-homocysteine + H(2)O <=> L-homocysteine + adenosine
Cofactor(s)
NAD(+).
Comment(s)
The NAD(+) cofactor appears to bring about a transient oxidation at C-3' of the 5'-deoxyadenosine residue, thus labilizing the thioether bond cf. EC 5.5.1.4.
Cross-references
PROSITEPDOC00603
BRENDA3.3.1.1
EC2PDB3.3.1.1
ExplorEnz3.3.1.1
PRIAM enzyme-specific profiles3.3.1.1
KEGG Ligand Database for Enzyme Nomenclature3.3.1.1
IUBMB Enzyme Nomenclature3.3.1.1
IntEnz3.3.1.1
MEDLINEFind literature relating to 3.3.1.1
MetaCyc3.3.1.1
UniProtKB/Swiss-Prot
O23255, SAHH1_ARATH;  P84533, SAHH1_POPEU;  Q9LK36, SAHH2_ARATH;  
P50245, SAHH2_DROME;  P84532, SAHH2_POPEU;  A6QLP2, SAHH3_BOVIN;  
Q96HN2, SAHH3_HUMAN;  Q68FL4, SAHH3_MOUSE;  Q5R889, SAHH3_PONAB;  
P51893, SAHHA_XENLA;  O93477, SAHHB_XENLA;  A1TUG3, SAHH_ACIAC;  
Q6FA43, SAHH_ACIAD;  B9MD45, SAHH_ACIET;  A1W3P0, SAHH_ACISJ;  
Q9YEF2, SAHH_AERPE;  Q8UJ99, SAHH_AGRFC;  B9JG53, SAHH_AGRRK;  
O76757, SAHH_ANOGA;  O67240, SAHH_AQUAE;  O28279, SAHH_ARCFU;  
Q5P6B7, SAHH_AROAE;  Q64MT2, SAHH_BACFR;  Q8A407, SAHH_BACTN;  
Q6G584, SAHH_BARHE;  Q6G1D6, SAHH_BARQU;  A9IL83, SAHH_BART1;  
Q6MNC0, SAHH_BDEBA;  Q7WQX5, SAHH_BORBR;  Q7W1Z7, SAHH_BORPA;  
A9IGY5, SAHH_BORPD;  Q7VUL8, SAHH_BORPE;  Q3MHL4, SAHH_BOVIN;  
Q89HP6, SAHH_BRADU;  A0A087WNH6, SAHH_BRAEL;  A5ENA7, SAHH_BRASB;  
B2S994, SAHH_BRUA1;  Q2YQX8, SAHH_BRUA2;  Q57AG3, SAHH_BRUAB;  
A9M9T1, SAHH_BRUC2;  C0RFY3, SAHH_BRUMB;  Q8YE49, SAHH_BRUME;  
A5VT52, SAHH_BRUO2;  B0CJJ7, SAHH_BRUSI;  Q8FXZ7, SAHH_BRUSU;  
A3MQW7, SAHH_BURM7;  A2S6W2, SAHH_BURM9;  Q62G22, SAHH_BURMA;  
A1V8Z2, SAHH_BURMS;  A3P0L8, SAHH_BURP0;  Q3JY79, SAHH_BURP1;  
A3NER1, SAHH_BURP6;  Q63PT2, SAHH_BURPS;  Q2STU0, SAHH_BURTA;  
P27604, SAHH_CAEEL;  P83783, SAHH_CANAL;  P35007, SAHH_CATRO;  
Q9ABH0, SAHH_CAUCR;  Q11CD0, SAHH_CHESB;  Q3AQC2, SAHH_CHLCH;  
B3EDY3, SAHH_CHLL2;  Q3B532, SAHH_CHLL7;  B3QMF5, SAHH_CHLP8;  
A1BEZ2, SAHH_CHLPD;  A4SF77, SAHH_CHLPM;  Q8KEG8, SAHH_CHLTE;  
Q7NZF7, SAHH_CHRVO;  P61456, SAHH_CORDI;  Q8FRJ4, SAHH_COREF;  
A4QC87, SAHH_CORGB;  Q8NSC4, SAHH_CORGL;  B6J6H1, SAHH_COXB1;  
B6J3R0, SAHH_COXB2;  A9KD88, SAHH_COXBN;  Q83A77, SAHH_COXBU;  
Q1LS20, SAHH_CUPMC;  Q0KF25, SAHH_CUPNH;  Q476T8, SAHH_CUPNJ;  
B2AGG2, SAHH_CUPTR;  B7K8X6, SAHH_CYAP7;  A9C184, SAHH_DELAS;  
C6C1F4, SAHH_DESAD;  Q30WL8, SAHH_DESAG;  Q72EH1, SAHH_DESVH;  
B8DR41, SAHH_DESVM;  A1VFZ7, SAHH_DESVV;  P10819, SAHH_DICDI;  
Q27580, SAHH_DROME;  A5FJK3, SAHH_FLAJ1;  A6GW32, SAHH_FLAPJ;  
P61617, SAHH_GEOSL;  Q7NGI6, SAHH_GLOVI;  Q0BW40, SAHH_GRABC;  
A0M5W6, SAHH_GRAFK;  Q2SLT4, SAHH_HAHCH;  A1WXM7, SAHH_HALHL;  
B0R7F2, SAHH_HALS3;  Q9HN50, SAHH_HALSA;  G0LFB0, SAHH_HALWC;  
Q18EV6, SAHH_HALWD;  A4G975, SAHH_HERAR;  P23526, SAHH_HUMAN;  
Q0C427, SAHH_HYPNA;  A6T2Y9, SAHH_JANMA;  P36889, SAHH_LEIDO;  
Q04NN6, SAHH_LEPBJ;  Q04WX0, SAHH_LEPBL;  B1Y647, SAHH_LEPCP;  
Q75FU8, SAHH_LEPIC;  Q8EXV1, SAHH_LEPIN;  Q9SP37, SAHH_LUPLU;  
Q4R596, SAHH_MACFA;  Q0ALW1, SAHH_MARMM;  P50246, SAHH_MEDSA;  
P93253, SAHH_MESCR;  Q8TRA5, SAHH_METAC;  B7KSJ4, SAHH_METC4;  
Q60CG8, SAHH_METCA;  A9VYP7, SAHH_METEP;  Q58783, SAHH_METJA;  
P58855, SAHH_METKA;  Q8PUQ4, SAHH_METMA;  Q6LYR8, SAHH_METMP;  
B8IPU4, SAHH_METNO;  B1ZLX0, SAHH_METPB;  A2SL00, SAHH_METPP;  
B0UM37, SAHH_METS4;  O27673, SAHH_METTH;  P50247, SAHH_MOUSE;  
Q7TWW7, SAHH_MYCBO;  A1KNQ0, SAHH_MYCBP;  C1AH22, SAHH_MYCBT;  
B8ZQE9, SAHH_MYCLB;  Q9CCJ4, SAHH_MYCLE;  B2HEP6, SAHH_MYCMM;  
Q73UK6, SAHH_MYCPA;  A4ZHR8, SAHH_MYCS2;  A3PW97, SAHH_MYCSJ;  
A1UCK8, SAHH_MYCSK;  Q1BCD6, SAHH_MYCSS;  A5U7S2, SAHH_MYCTA;  
P9WGV2, SAHH_MYCTO;  P9WGV3, SAHH_MYCTU;  A0PRF5, SAHH_MYCUA;  
Q1CY84, SAHH_MYXXD;  P68172, SAHH_NICSY;  Q0AEV8, SAHH_NITEC;  
Q82WL1, SAHH_NITEU;  Q5YQS7, SAHH_NOCFA;  Q8YX05, SAHH_NOSS1;  
Q2G6T1, SAHH_NOVAD;  A6WX40, SAHH_OCHA4;  B2JIP4, SAHH_PARP8;  
B2T6X2, SAHH_PARPJ;  Q13T36, SAHH_PARXL;  Q3A392, SAHH_PELCD;  
B4SD43, SAHH_PELPB;  Q01781, SAHH_PETCR;  P50249, SAHH_PHASS;  
Q710C4, SAHH_PIG;  Q4XZZ5, SAHH_PLACH;  P50250, SAHH_PLAF7;  
Q7RKK8, SAHH_PLAYO;  Q12663, SAHH_PNECA;  A4T0E9, SAHH_POLAQ;  
B1XSH8, SAHH_POLNS;  A3PFB5, SAHH_PROM0;  A8G7D1, SAHH_PROM2;  
A2C620, SAHH_PROM3;  A9BD69, SAHH_PROM4;  Q318B6, SAHH_PROM9;  
Q7V9P3, SAHH_PROMA;  Q7V926, SAHH_PROMM;  Q7UZN3, SAHH_PROMP;  
Q48PB5, SAHH_PSE14;  B7V419, SAHH_PSEA8;  Q02TY0, SAHH_PSEAB;  
Q9I685, SAHH_PSEAE;  Q1I3W5, SAHH_PSEE4;  Q4K4H7, SAHH_PSEF5;  
C3K3G6, SAHH_PSEFS;  A4XPF3, SAHH_PSEMY;  A5WA09, SAHH_PSEP1;  
Q3K5D7, SAHH_PSEPF;  B0KM00, SAHH_PSEPG;  B1J2Y8, SAHH_PSEPW;  
Q87V73, SAHH_PSESM;  Q4ZZ92, SAHH_PSEU2;  A4VRF7, SAHH_PSEU5;  
Q9UYK5, SAHH_PYRAB;  Q8ZTQ7, SAHH_PYRAE;  P50251, SAHH_PYRFU;  
O58275, SAHH_PYRHO;  B2U774, SAHH_RALPJ;  Q8Y387, SAHH_RALSO;  
P10760, SAHH_RAT;  B3PVW2, SAHH_RHIE6;  Q2KE72, SAHH_RHIEC;  
Q1MNC6, SAHH_RHIL3;  Q98CM3, SAHH_RHILO;  B5ZV80, SAHH_RHILW;  
Q92TC1, SAHH_RHIME;  Q7TTZ5, SAHH_RHOBA;  P28183, SAHH_RHOCB;  
Q2IZR1, SAHH_RHOP2;  Q6N2N5, SAHH_RHOPA;  Q13AQ5, SAHH_RHOPS;  
B3QJT3, SAHH_RHOPT;  O50562, SAHH_RHOSH;  Q9ZNA5, SAHH_ROSDO;  
O13639, SAHH_SCHPO;  A6UEJ1, SAHH_SINMW;  Q9SWF5, SAHH_SOLLC;  
Q01VU1, SAHH_SOLUE;  Q1GWT5, SAHH_SPHAL;  Q936D6, SAHH_STRAA;  
Q82DC9, SAHH_STRAW;  Q8GGL7, SAHH_STRAZ;  Q9KZM1, SAHH_STRCO;  
P26799, SAHH_STRFR;  B1VUW6, SAHH_STRGG;  Q4JAZ7, SAHH_SULAC;  
P50252, SAHH_SULSO;  Q975T0, SAHH_SULTO;  A5GI30, SAHH_SYNPW;  
Q7U9Y3, SAHH_SYNPX;  Q0IDX7, SAHH_SYNS3;  Q3B0K7, SAHH_SYNS9;  
Q3ANF4, SAHH_SYNSC;  P74008, SAHH_SYNY3;  Q9HKX4, SAHH_THEAC;  
Q8DGC8, SAHH_THEEB;  Q5JED2, SAHH_THEKO;  O51933, SAHH_THEMA;  
Q979Z4, SAHH_THEVO;  P68173, SAHH_TOBAC;  P51540, SAHH_TRIVA;  
C5CM29, SAHH_VARPS;  P32112, SAHH_WHEAT;  Q8PP84, SAHH_XANAC;  
Q3BXC6, SAHH_XANC5;  Q4UQZ8, SAHH_XANC8;  Q8PCH5, SAHH_XANCP;  
Q2NZE3, SAHH_XANOM;  B2SPN6, SAHH_XANOP;  B2I7N4, SAHH_XYLF2;  
Q9PEJ1, SAHH_XYLFA;  B0U232, SAHH_XYLFM;  Q87EI8, SAHH_XYLFT;  
P39954, SAHH_YEAST;  Q5NR48, SAHH_ZYMMO;  

View entry in original ENZYME format
View entry in raw text format (no links)

All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.3.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.3.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.-.-.-