ENZYME entry: EC 3.3.2.11
| Accepted Name |
|---|
| Cholesterol-5,6-oxide hydrolase.
|
| Alternative Name(s) |
|---|
| ChEH. |
| Cholesterol-epoxide hydrolase. |
| Reaction catalysed |
|---|
- 5,6-alpha-epoxy-5-alpha-cholestan-3-beta-ol + H(2)O <=> cholestane-3-beta,5-alpha,6-beta-triol
- 5,6-beta-epoxy-5-beta-cholestan-3-beta-ol + H(2)O <=> cholestane-3-beta,5-alpha,6-beta-triol
|
| Comment(s) |
|---|
- The enzyme appears to work equally well with both diastereoisomers of
cholesterol 5,6-epoxide.
- The product is a competitive inhibitor of the reaction.
|
| Cross-references |
|---|
| BRENDA | 3.3.2.11 |
| EC2PDB | 3.3.2.11 |
| ExplorEnz | 3.3.2.11 |
| PRIAM enzyme-specific profiles | 3.3.2.11 |
| KEGG Ligand Database for Enzyme Nomenclature | 3.3.2.11 |
| IUBMB Enzyme Nomenclature | 3.3.2.11 |
| IntEnz | 3.3.2.11 |
| MEDLINE | Find literature relating to 3.3.2.11 |
| MetaCyc | 3.3.2.11 |
View entry in original ENZYME format
View entry in raw text format (no links)
All
ENZYME /
UniProtKB/Swiss-Prot entries corresponding to 3.3.2.-
All
ENZYME /
UniProtKB/Swiss-Prot entries corresponding to 3.3.-.-
All
ENZYME /
UniProtKB/Swiss-Prot entries corresponding to 3.-.-.-