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ENZYME entry: EC 3.4.11.23

Accepted Name
PepB aminopeptidase.
Alternative Name(s)
Aminopeptidase B.
Peptidase B.
Reaction catalysed
Release of an N-terminal amino acid, Xaa, from a peptide or arylamide. Xaa is preferably Glu or Asp but may be other amino acids, including Leu, Met, His, Cys and Gln
Comment(s)
  • A 270-kDa protein composed of six 46.3-kDa subunits.
  • The pH optimum is in the alkaline range and activity is stimulated by KCl.
  • Belongs to peptidase family M17.
Cross-references
BRENDA3.4.11.23
EC2PDB3.4.11.23
ExplorEnz3.4.11.23
PRIAM enzyme-specific profiles3.4.11.23
KEGG Ligand Database for Enzyme Nomenclature3.4.11.23
IUBMB Enzyme Nomenclature3.4.11.23
IntEnz3.4.11.23
MEDLINEFind literature relating to 3.4.11.23
MetaCyc3.4.11.23
UniProtKB/Swiss-Prot
A8AD60, PEPB_CITK8;  A7MGW9, PEPB_CROS8;  A7ZPW6, PEPB_ECO24;  
B7UGW9, PEPB_ECO27;  B7MI07, PEPB_ECO45;  B7LDB5, PEPB_ECO55;  
P58473, PEPB_ECO57;  B5Z0Z6, PEPB_ECO5E;  B7NRH2, PEPB_ECO7I;  
B7MYF7, PEPB_ECO81;  B7M7M6, PEPB_ECO8A;  C4ZX98, PEPB_ECOBW;  
B1XAZ8, PEPB_ECODH;  A8A329, PEPB_ECOHS;  A1AE61, PEPB_ECOK1;  
Q0TEW2, PEPB_ECOL5;  Q8FF47, PEPB_ECOL6;  B1IWD8, PEPB_ECOLC;  
P37095, PEPB_ECOLI;  B7N6B0, PEPB_ECOLU;  B6I595, PEPB_ECOSE;  
B1LNH8, PEPB_ECOSM;  Q1R8K9, PEPB_ECOUT;  A4WDA4, PEPB_ENT38;  
B7LKB6, PEPB_ESCF3;  Q4QM33, PEPB_HAEI8;  P58474, PEPB_HAEIN;  
B5XNK4, PEPB_KLEP3;  A6TCE4, PEPB_KLEP7;  Q9CM16, PEPB_PASMU;  
Q6D266, PEPB_PECAS;  C6DBI4, PEPB_PECCP;  Q7N231, PEPB_PHOLL;  
B5F1B3, PEPB_SALA4;  A9MHK1, PEPB_SALAR;  Q57LH5, PEPB_SALCH;  
B5FR78, PEPB_SALDC;  B5R595, PEPB_SALEP;  B5RD05, PEPB_SALG2;  
B4T0R5, PEPB_SALNS;  A9N1Y3, PEPB_SALPB;  C0PYL4, PEPB_SALPC;  
Q8Z4N3, PEPB_SALTI;  Q9RF52, PEPB_SALTY;  A8GHX6, PEPB_SERP5;  
B2TXU8, PEPB_SHIB3;  Q31XW7, PEPB_SHIBS;  Q32D41, PEPB_SHIDS;  
Q0T1Z6, PEPB_SHIF8;  Q83QK5, PEPB_SHIFL;  Q3YZ29, PEPB_SHISS;  
A7MU37, PEPB_VIBCB;  Q9KTX5, PEPB_VIBCH;  Q87S21, PEPB_VIBPA;  
B7VJT3, PEPB_VIBTL;  Q8DEZ4, PEPB_VIBVU;  Q7MNF5, PEPB_VIBVY;  
A7FFX8, PEPB_YERP3;  Q1C5H7, PEPB_YERPA;  B2K9R0, PEPB_YERPB;  
P58475, PEPB_YERPE;  A9R811, PEPB_YERPG;  Q1CKA2, PEPB_YERPN;  
A4TMU7, PEPB_YERPP;  Q667Y8, PEPB_YERPS;  B1JRZ6, PEPB_YERPY;  

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