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ENZYME

ENZYME entry: EC 3.4.14.1

Accepted Name
dipeptidyl-peptidase I
Alternative Name(s)
cathepsin C
cathepsin J
dipeptidyl aminopeptidase I
dipeptidyl transferase
Reaction catalysed
Release of an N-terminal dipeptide, Xaa-Yaa-|-Zaa-, except when Xaa is Arg or Lys, or Yaa or Zaa is Pro
Comment(s)
  • Also polymerizes dipeptide amides, arylamides and esters at neutral pH.
  • Cl(-)-dependent lysosomal cysteine-type peptidase.
  • Belongs to peptidase family C1.
  • Formerly EC 3.4.4.9.
Cross-references
BRENDA3.4.14.1
EC2PDB3.4.14.1
ExplorEnz3.4.14.1
PRIAM enzyme-specific profiles3.4.14.1
KEGG Ligand Database for Enzyme Nomenclature3.4.14.1
IUBMB Enzyme Nomenclature3.4.14.1
IntEnz3.4.14.1
MEDLINEFind literature relating to 3.4.14.1
MetaCyc3.4.14.1
Rhea expert-curated reactions3.4.14.1
UniProtKB/Swiss-Prot
Q3ZCJ8, CATC_BOVINO97578, CATC_CANLFP53634, CATC_HUMAN
Q60HG6, CATC_MACFAP97821, CATC_MOUSEQ5RB02, CATC_PONAB
P80067, CATC_RATQ8IIJ9, DPAP1_PLAF7

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