ENZYME entry: EC 3.4.14.2

Accepted Name
Dipeptidyl-peptidase II.
Alternative Name(s)
Carboxytripeptidase.
Dipeptidyl aminopeptidase II.
Dipeptidyl arylamidase II.
DPP II.
Quiescent cell proline dipeptidase.
Reaction catalysed
Release of an N-terminal dipeptide, Xaa-Yaa-|-, preferentially when Yaa is Ala or Pro. Substrates are oligopeptides, preferentially tripeptides
Comment(s)
  • A lysosomal serine-type peptidase maximally active at acidic pH.
  • Cleaves Lys-Ala-naphthylamide.
  • Belongs to peptidase family S28.
Cross-references
BRENDA3.4.14.2
EC2PDB3.4.14.2
ExplorEnz3.4.14.2
PRIAM enzyme-specific profiles3.4.14.2
KEGG Ligand Database for Enzyme Nomenclature3.4.14.2
IUBMB Enzyme Nomenclature3.4.14.2
IntEnz3.4.14.2
MEDLINEFind literature relating to 3.4.14.2
MetaCyc3.4.14.2
UniProtKB/Swiss-Prot
Q9UHL4, DPP2_HUMAN;  Q9ET22, DPP2_MOUSE;  Q9EPB1, DPP2_RAT;  

View entry in original ENZYME format
View entry in raw text format (no links)

All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.4.14.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.4.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.-.-.-