ID   3.4.15.1
DE   Peptidyl-dipeptidase A.
AN   ACE.
AN   Angiotensin I-converting enzyme.
AN   Carboxycathepsin.
AN   Dipeptidyl carboxypeptidase I.
AN   Kininase II.
AN   Peptidase P.
AN   Peptidyl dipeptidase I.
CA   Release of a C-terminal dipeptide, oligopeptide-|-Xaa-Yaa, when Xaa is
CA   not Pro, and Yaa is neither Asp nor Glu. Thus, conversion of angiotensin
CA   I to angiotensin II, with increase in vasoconstrictor activity, but no
CA   action on angiotensin II.
CF   Zinc.
CC   -!- Cl(-)-dependent.
CC   -!- A glycoprotein that is generally membrane-bound.
CC   -!- Active at neutral pH.
CC   -!- Only single dipeptides are released from angiotensin I and bradykinin
CC       because of the lack of activity on bonds involving proline.
CC   -!- Belongs to peptidase family M2.
PR   PROSITE; PDOC00129;
DR   Q9VLJ6, ACER_DROME ;  P12820, ACE_BOVIN  ;  Q10751, ACE_CHICK  ;
DR   Q10714, ACE_DROME  ;  Q10715, ACE_HAEIX  ;  P12821, ACE_HUMAN  ;
DR   Q50JE5, ACE_MESAU  ;  P09470, ACE_MOUSE  ;  Q9GLN7, ACE_PANTR  ;
DR   P12822, ACE_RABIT  ;  P47820, ACE_RAT    ;  Q6Q4G4, ACE_THETS  ;
//