ENZYME entry: EC 3.4.16.2

Accepted Name
Lysosomal Pro-Xaa carboxypeptidase.
Alternative Name(s)
Angiotensinase C.
Lysosomal carboxypeptidase C.
Lysosomal Pro-X carboxypeptidase.
Proline carboxypeptidase.
Prolyl carboxypeptidase.
Reaction catalysed
Cleavage of a -Pro-|-Xaa bond to release a C-terminal amino acid
Comment(s)
  • A lysosomal peptidase active at acidic pH that inactivates angiotensin II.
  • Inhibited by diisopropyl fluorophosphate.
  • Belongs to peptidase family S28.
  • Formerly EC 3.4.12.4.
Cross-references
BRENDA3.4.16.2
EC2PDB3.4.16.2
ExplorEnz3.4.16.2
PRIAM enzyme-specific profiles3.4.16.2
KEGG Ligand Database for Enzyme Nomenclature3.4.16.2
IUBMB Enzyme Nomenclature3.4.16.2
IntEnz3.4.16.2
MEDLINEFind literature relating to 3.4.16.2
MetaCyc3.4.16.2
UniProtKB/Swiss-Prot
Q2TA14, PCP_BOVIN;  P42785, PCP_HUMAN;  Q7TMR0, PCP_MOUSE;  
Q5RBU7, PCP_PONAB;  

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