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ENZYME entry: EC 3.4.16.5

Accepted Name
Carboxypeptidase C.
Alternative Name(s)
Carboxypeptidase Y.
Cathepsin A.
Lysosomal protective protein.
Serine-type carboxypeptidase I.
Reaction catalysed
Release of a C-terminal amino acid with broad specificity
Comment(s)
  • Carboxypeptidases of broad specificity with optimum pH 4.5-6.0, inhibited by the action of diisopropyl fluorophosphate, and sensitive to thiol-blocking reagents.
  • This enzyme is probably also identical to lysosomal tyrosine carboxypeptidase.
  • Belongs to peptidase family S10.
  • Formerly EC 3.4.12.1, EC 3.4.12.12, EC 3.4.16.1, EC 3.4.16.3 and EC 3.4.21.13.
Cross-references
PROSITEPDOC00122
BRENDA3.4.16.5
EC2PDB3.4.16.5
ExplorEnz3.4.16.5
PRIAM enzyme-specific profiles3.4.16.5
KEGG Ligand Database for Enzyme Nomenclature3.4.16.5
IUBMB Enzyme Nomenclature3.4.16.5
IntEnz3.4.16.5
MEDLINEFind literature relating to 3.4.16.5
MetaCyc3.4.16.5
UniProtKB/Swiss-Prot
P07519, CBP1_HORVU;  P37890, CBP1_ORYSJ;  P21529, CBP3_HORVU;  
P37891, CBP3_ORYSJ;  P11515, CBP3_WHEAT;  C0NX46, CBPYA_AJECG;  
A6RGA0, CBPYA_AJECN;  C5GEU5, CBPYA_AJEDR;  D4AZ71, CBPYA_ARTBC;  
E4USS9, CBPYA_ARTGP;  C5FWJ1, CBPYA_ARTOC;  A1CUJ5, CBPYA_ASPCL;  
B8NXS9, CBPYA_ASPFN;  Q5VJG9, CBPYA_ASPFU;  A5AB21, CBPYA_ASPNC;  
Q2TYA1, CBPYA_ASPOR;  Q0CSD3, CBPYA_ASPTN;  C5K1Y9, CBPYA_BLAGS;  
A6RUD7, CBPYA_BOTFB;  Q2H9G6, CBPYA_CHAGB;  C5P212, CBPYA_COCP7;  
E3QR43, CBPYA_COLGM;  Q96VC4, CBPYA_EMENI;  E5A7I6, CBPYA_LEPMJ;  
A4RPY8, CBPYA_MAGO7;  C7YQJ2, CBPYA_NECH7;  A1DP75, CBPYA_NEOFI;  
Q7RXW8, CBPYA_NEUCR;  C1GXD8, CBPYA_PARBA;  C1GG77, CBPYA_PARBD;  
C0SGX7, CBPYA_PARBP;  B6HPP6, CBPYA_PENRW;  Q0V1R1, CBPYA_PHANO;  
B2AWD5, CBPYA_PODAN;  B2WKF1, CBPYA_PYRTR;  A7F4H5, CBPYA_SCLS1;  
D1ZG13, CBPYA_SORMK;  B6QAN5, CBPYA_TALMQ;  B8M044, CBPYA_TALSN;  
B8XGR4, CBPYA_TRIEQ;  Q5J6J0, CBPYA_TRIRU;  A5YCB8, CBPYA_TRITO;  
D4DLI1, CBPYA_TRIVH;  C4JNM2, CBPYA_UNCRE;  D4ANB6, CBPYB_ARTBC;  
P30574, CBPY_CANAX;  P52710, CBPY_KOMPG;  O13849, CBPY_SCHPO;  
P00729, CBPY_YEAST;  Q3MI05, PPGB_BOVIN;  P10619, PPGB_HUMAN;  
P16675, PPGB_MOUSE;  D4AQ54, SCPC_ARTBC;  D4B0Q6, SCPD_ARTBC;  
D4AZG9, SCPE_ARTBC;  D4ASE6, SCPF_ARTBC;  

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All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.4.16.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.4.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.-.-.-