ENZYME entry: EC 3.4.17.10

Accepted Name
Carboxypeptidase E.
Alternative Name(s)
Carboxypeptidase H.
Enkephalin convertase.
Reaction catalysed
Release of C-terminal arginine or lysine residues from polypeptides
Cofactor(s)
Zn(2+).
Comment(s)
  • Activated by Co(2+).
  • Inhibited by 1,10-phenanthroline and other chelating agents.
  • pH optimum 5.6.
  • Located in storage granules of secretory cells, and active in processing of protein hormones and bioactive peptides.
  • Distinct from EC 3.4.17.2 and EC 3.4.17.3.
  • Belongs to peptidase family M14.
Cross-references
PROSITEPDOC00123
BRENDA3.4.17.10
EC2PDB3.4.17.10
ExplorEnz3.4.17.10
PRIAM enzyme-specific profiles3.4.17.10
KEGG Ligand Database for Enzyme Nomenclature3.4.17.10
IUBMB Enzyme Nomenclature3.4.17.10
IntEnz3.4.17.10
MEDLINEFind literature relating to 3.4.17.10
MetaCyc3.4.17.10
UniProtKB/Swiss-Prot
P04836, CBPE_BOVIN;  P16870, CBPE_HUMAN;  P37892, CBPE_LOPAM;  
Q4R4M3, CBPE_MACFA;  Q00493, CBPE_MOUSE;  A5A6K7, CBPE_PANTR;  
P15087, CBPE_RAT;  

View entry in original ENZYME format
View entry in raw text format (no links)

All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.4.17.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.4.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.-.-.-