ENZYME entry: EC 3.4.17.20
| Accepted Name |
|---|
| Carboxypeptidase U.
|
| Alternative Name(s) |
|---|
| Arginine carboxypeptidase. |
| Carboxypeptidase B2. |
| Carboxypeptidase R. |
| Plasma carboxypeptidase B. |
| TAFI. |
| Thrombin-activatable fibrinolysis inhibitor. |
| Reaction catalysed |
|---|
| Release of C-terminal Arg and Lys from a polypeptide |
| Cofactor(s) |
|---|
| Zinc.
|
| Comment(s) |
|---|
- Pro-carboxypeptidase U in plasma is activated by thrombin or plasmin
during clotting to form the unstable carboxypeptidase U.
- Activity similar to that of the more stable lysine carboxypeptidase,
except no preference is shown for Lys over Arg.
- Belongs to peptidase family M14.
|
| Cross-references |
|---|
| BRENDA | 3.4.17.20 |
| EC2PDB | 3.4.17.20 |
| ExplorEnz | 3.4.17.20 |
| PRIAM enzyme-specific profiles | 3.4.17.20 |
| KEGG Ligand Database for Enzyme Nomenclature | 3.4.17.20 |
| IUBMB Enzyme Nomenclature | 3.4.17.20 |
| IntEnz | 3.4.17.20 |
| MEDLINE | Find literature relating to 3.4.17.20 |
| MetaCyc | 3.4.17.20 |
| UniProtKB/Swiss-Prot |
|
View entry in original ENZYME format
View entry in raw text format (no links)
All UniProtKB/Swiss-Prot
entries referenced
in this entry, with possibility to download in different formats, align etc.
All
ENZYME /
UniProtKB/Swiss-Prot entries corresponding to 3.4.17.-
All
ENZYME /
UniProtKB/Swiss-Prot entries corresponding to 3.4.-.-
All
ENZYME /
UniProtKB/Swiss-Prot entries corresponding to 3.-.-.-