ENZYME entry: EC 3.4.17.8
| Accepted Name |
|---|
| Muramoylpentapeptide carboxypeptidase.
|
| Alternative Name(s) |
|---|
| Carboxypeptidase D-alanyl-D-alanine. |
| D-alanine carboxypeptidase. |
| D-alanine-D-alanine-carboxypeptidase. |
| D-alanyl-D-alanine carboxypeptidase. |
| D-alanyl-D-alanine peptidase. |
| DD-carboxypeptidase. |
| DD-peptidase. |
| PBP5. |
| Penicillin binding protein 5. |
| UDP-N-acetylmuramoyl-tetrapeptidyl-D-alanine alanine-hydrolase. |
| Reaction catalysed |
|---|
| Cleavage of the bond UDP-N-acetylmuramoyl-L-alanyl-D-gamma-glutamyl-6-carboxy-L-lysyl-D-alanyl-|-D-alanine |
| Cofactor(s) |
|---|
| Zinc.
|
| Comment(s) |
|---|
- Does not cleave the C-terminal D-alanine from the product of the
above reaction, UDP-N-acetyl-muramoyl-L-alanyl-D-gamma-glutamyl-6-
carboxy-L-lysyl-D-alanine.
- Competitively inhibited by penicillins and cephalosporins.
- Belongs to peptidase family M15.
- Formerly EC 3.4.12.6.
|
| Cross-references |
|---|
| BRENDA | 3.4.17.8 |
| EC2PDB | 3.4.17.8 |
| ExplorEnz | 3.4.17.8 |
| PRIAM enzyme-specific profiles | 3.4.17.8 |
| KEGG Ligand Database for Enzyme Nomenclature | 3.4.17.8 |
| IUBMB Enzyme Nomenclature | 3.4.17.8 |
| IntEnz | 3.4.17.8 |
| MEDLINE | Find literature relating to 3.4.17.8 |
| MetaCyc | 3.4.17.8 |
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ENZYME /
UniProtKB/Swiss-Prot entries corresponding to 3.4.17.-
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ENZYME /
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