To improve security and privacy, we are moving our web pages and services from HTTP to HTTPS.
To give users of web services time to transition to HTTPS, we will support separate HTTP and HTTPS services until the end of 2017.
From January 2018 most HTTP traffic will be automatically redirected to HTTPS. [more...]
View this page in https

ENZYME entry: EC

Accepted Name
Alternative Name(s)
Dictyostelium discoideum aspartic proteinase.
Dictyostelium discoideum aspartic proteinase E.
Physarum aspartic proteinase.
Physarum flavicomum aspartic proteinase.
Physarum polycephalum acid proteinase.
Reaction catalysed
Milk clotting activity. Preferential cleavage of 8-Gly-|-Ser-9 in B chain of insulin most rapidly, followed by 11-Leu-|-Val-12, 19-Cys(SO(3)H)-|-Gly and 24-Phe-|-Phe-25. No action on Ac-Phe-Tyr(I)(2)
  • From the slime mold Physarum polycephalum.
  • Is not inhibited by pepstatin, but is blocked by methyl 2-diazoacetamidohexanoate.
  • Closely similar enzymes are found in Dictyostelium discoideum and P.flavicomum.
  • Belongs to peptidase family S53.
  • Formerly EC, EC and EC
PRIAM enzyme-specific profiles3.4.21.103
KEGG Ligand Database for Enzyme Nomenclature3.4.21.103
IUBMB Enzyme Nomenclature3.4.21.103
MEDLINEFind literature relating to

View entry in original ENZYME format
View entry in raw text format (no links)

All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.4.21.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.4.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.-.-.-