ID   3.4.21.115
DE   infectious pancreatic necrosis birnavirus Vp4 peptidase.
AN   infectious pancreatic necrosis virus protease.
AN   IPNV Vp4 peptidase.
AN   IPNV Vp4 protease.
AN   NS-associated protease.
AN   NS protease.
AN   Vp4 protease.
CA   Cleaves the (Ser/Thr)-Xaa-Ala-|-(Ser/Ala)-Gly motif in the polyprotein
CA   NH2-pVP2-VP4-VP3-COOH of infectious pancreatic necrosis virus at the
CA   pVP2-VP4 and VP4-VP3 junctions.
CC   -!- Infectious pancreatic necrosis virus (IPNV) is a birnavirus that
CC       causes an acute, contagious disease in young salmonid fish.
CC   -!- As with most viruses that infect eukaryotic cells, the proteolytic
CC       processing of viral precursor proteins is a crucial step in the life
CC       cycle of this virus.
CC   -!- pVP2 is converted into VP2 by cleavage near the carboxy end of pVP2;
CC       this cleavage is most likely due to host-cell proteases rather than
CC       VP4.
CC   -!- Differs from most serine peptidases in not having the catalytic triad
CC       Ser-His-Asp.
CC   -!- Belongs to peptidase family S50.
//