Expasy logo

ENZYME

ENZYME entry: EC 3.4.21.26

Accepted Name
prolyl oligopeptidase
Alternative Name(s)
post-proline cleaving enzyme
post-proline endopeptidase
prolyl endopeptidase
Reaction catalysed
Hydrolysis of Pro-|-Xaa >> Ala-|-Xaa in oligopeptides
Comment(s)
  • Found in vertebrates, plants and Flavobacterium.
  • Generally cytosolic, commonly activated by thiol compounds.
  • Belongs to peptidase family S9A.
  • Formerly EC 3.4.22.18.
Cross-references
BRENDA3.4.21.26
EC2PDB3.4.21.26
ExplorEnz3.4.21.26
PRIAM enzyme-specific profiles3.4.21.26
KEGG Ligand Database for Enzyme Nomenclature3.4.21.26
IUBMB Enzyme Nomenclature3.4.21.26
IntEnz3.4.21.26
MEDLINEFind literature relating to 3.4.21.26
MetaCyc3.4.21.26
Rhea expert-curated reactions3.4.21.26
UniProtKB/Swiss-Prot
A0A4S8L6U5, DBIP_DENBCA0A1Q3EPF5, LEDP_LENEDC0HLV2, NEPRN_NEPVE
P9WEN5, OPHP_OMPOLE2JFG1, POPA_AMABIH2E7Q7, POPA_GALM3
E2JFG2, POPB_AMABIH2E7Q8, POPB_GALM3Q06903, PPCE_AERHY
Q9XTA2, PPCE_BOVINQ86AS5, PPCE_DICDIP27028, PPCE_ELIME
P48147, PPCE_HUMANQ9QUR6, PPCE_MOUSEP23687, PPCE_PIG
O70196, PPCE_RATP27195, PPCF_ELIMRA5D7B7, SEPR_BOVIN
Q12884, SEPR_HUMANP97321, SEPR_MOUSE

View entry in original ENZYME format
View entry in raw text format (no links)
All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.4.21.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.4.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.-.-.-