ENZYME entry: EC 3.4.21.37
| Accepted Name |
|---|
| Leukocyte elastase.
|
| Alternative Name(s) |
|---|
| Bone marrow serine protease. |
| Lysosomal elastase. |
| Medullasin. |
| Neutrophil elastase. |
| Reaction catalysed |
|---|
| Hydrolysis of proteins, including elastin. Preferential cleavage: Val-|-Xaa > Ala-|-Xaa |
| Comment(s) |
|---|
- Differs from pancreatic elastase in specificity on synthetic
substrates and in inhibitor sensitivity.
- Belongs to peptidase family S1.
- Formerly EC 3.4.4.7 and EC 3.4.21.11.
|
| Cross-references |
|---|
| PROSITE | PDOC00124 |
| BRENDA | 3.4.21.37 |
| EC2PDB | 3.4.21.37 |
| ExplorEnz | 3.4.21.37 |
| PRIAM enzyme-specific profiles | 3.4.21.37 |
| KEGG Ligand Database for Enzyme Nomenclature | 3.4.21.37 |
| IUBMB Enzyme Nomenclature | 3.4.21.37 |
| IntEnz | 3.4.21.37 |
| MEDLINE | Find literature relating to 3.4.21.37 |
| MetaCyc | 3.4.21.37 |
| UniProtKB/Swiss-Prot |
|
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