ID 3.4.21.37 DE leukocyte elastase. AN bone marrow serine protease. AN lysosomal elastase. AN medullasin. AN neutrophil elastase. CA Hydrolysis of proteins, including elastin. Preferential cleavage: CA Val-|-Xaa > Ala-|-Xaa. CC -!- Differs from pancreatic elastase in specificity on synthetic CC substrates and in inhibitor sensitivity. CC -!- Belongs to peptidase family S1. CC -!- Formerly EC 3.4.4.7 and EC 3.4.21.11. DR P08246, ELNE_HUMAN ; Q3UP87, ELNE_MOUSE ; //