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ENZYME entry: EC

Accepted Name
Coagulation factor XIIa.
Alternative Name(s)
Hageman factor.
Reaction catalysed
Selective cleavage of Arg-|-Ile bonds in factor VII to form factor VIIa and factor XI to form factor XIa
  • Also activates plasma prekallikrein and plasminogen.
  • Formed from the proenzyme, factor XII, by plasma kallikrein or factor XIIa.
  • Belongs to peptidase family S1.
PRIAM enzyme-specific profiles3.4.21.38
KEGG Ligand Database for Enzyme Nomenclature3.4.21.38
IUBMB Enzyme Nomenclature3.4.21.38
MEDLINEFind literature relating to
P98140, FA12_BOVIN;  Q04962, FA12_CAVPO;  P00748, FA12_HUMAN;  
Q80YC5, FA12_MOUSE;  O97507, FA12_PIG;  D3ZTE0, FA12_RAT;  

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.4.21.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.4.-.-
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