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ENZYME entry: EC 18.104.22.168
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|Complement subcomponent C1r.
|Selective cleavage of Lys(or Arg)-|-Ile bond in complement subcomponent C1s to form the active form of C1s (EC 22.214.171.124)|
- Activates C1s by proteolytic cleavage so that it can, in turn,
activate C2 and C4.
- Activated from proenzyme C1r in plasma by autocatalytic mechanism
during activation of the complement system by the 'classical' route.
- Belongs to peptidase family S1.
|PRIAM enzyme-specific profiles||126.96.36.199|
|KEGG Ligand Database for Enzyme Nomenclature||188.8.131.52|
|IUBMB Enzyme Nomenclature||184.108.40.206|
|MEDLINE||Find literature relating to 220.127.116.11|
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entries corresponding to 3.4.21.-
entries corresponding to 3.4.-.-
entries corresponding to 3.-.-.-