ENZYME entry: EC 3.4.21.45
| Accepted Name |
|---|
| Complement factor I.
|
| Alternative Name(s) |
|---|
| C3b inactivator. |
| C3b/C4b inactivator. |
| Complement component C3b inactivator. |
| Reaction catalysed |
|---|
| Inactivates complement subcomponents C3b, iC3b and C4b by proteolytic cleavage |
| Comment(s) |
|---|
- Cleavage of complement subcomponent C3b requires its binding to
cofactor H or complement receptor CR1; cleavage of iC3b requires
complement receptor CR1; cleavage of C4b requires C4b-binding
protein.
- Belongs to peptidase family S1.
|
| Cross-references |
|---|
| PROSITE | PDOC00124 |
| BRENDA | 3.4.21.45 |
| EC2PDB | 3.4.21.45 |
| ExplorEnz | 3.4.21.45 |
| PRIAM enzyme-specific profiles | 3.4.21.45 |
| KEGG Ligand Database for Enzyme Nomenclature | 3.4.21.45 |
| IUBMB Enzyme Nomenclature | 3.4.21.45 |
| IntEnz | 3.4.21.45 |
| MEDLINE | Find literature relating to 3.4.21.45 |
| MetaCyc | 3.4.21.45 |
| UniProtKB/Swiss-Prot |
|
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