ENZYME entry: EC 3.4.21.46
| Accepted Name |
|---|
| Complement factor D.
|
| Alternative Name(s) |
|---|
| C3 convertase activator. |
| C3 proactivator convertase. |
| Reaction catalysed |
|---|
| Selective cleavage of Arg-|-Lys bond in complement factor B when in complex with complement subcomponent C3b or with cobra venom factor |
| Comment(s) |
|---|
- A component of the alternative pathway of complement activation.
- This reaction is analogous to the activation of complement component
C2 by activated complement subcomponent C1s.
- Belongs to peptidase family S1.
|
| Cross-references |
|---|
| PROSITE | PDOC00124 |
| BRENDA | 3.4.21.46 |
| EC2PDB | 3.4.21.46 |
| ExplorEnz | 3.4.21.46 |
| PRIAM enzyme-specific profiles | 3.4.21.46 |
| KEGG Ligand Database for Enzyme Nomenclature | 3.4.21.46 |
| IUBMB Enzyme Nomenclature | 3.4.21.46 |
| IntEnz | 3.4.21.46 |
| MEDLINE | Find literature relating to 3.4.21.46 |
| MetaCyc | 3.4.21.46 |
| UniProtKB/Swiss-Prot |
|
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