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ENZYME entry: EC

Accepted Name
Complement factor D.
Alternative Name(s)
C3 convertase activator.
C3 proactivator convertase.
Reaction catalysed
Selective cleavage of Arg-|-Lys bond in complement factor B when in complex with complement subcomponent C3b or with cobra venom factor
  • A component of the alternative pathway of complement activation.
  • This reaction is analogous to the activation of complement component C2 by activated complement subcomponent C1s.
  • Belongs to peptidase family S1.
PRIAM enzyme-specific profiles3.4.21.46
KEGG Ligand Database for Enzyme Nomenclature3.4.21.46
IUBMB Enzyme Nomenclature3.4.21.46
MEDLINEFind literature relating to
P51779, CFAD_PIG;  P32038, CFAD_RAT;  

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All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.4.21.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.4.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.-.-.-