ENZYME entry: EC 3.4.21.5

Accepted Name
Thrombin.
Alternative Name(s)
Fibrinogenase.
Reaction catalysed
Selective cleavage of Arg-|-Gly bonds in fibrinogen to form fibrin and release fibrinopeptides A and B
Comment(s)
  • More selective than trypsin and plasmin.
  • Belongs to peptidase family S1.
  • Formerly EC 3.4.4.13.
Cross-references
PROSITEPDOC00124
BRENDA3.4.21.5
EC2PDB3.4.21.5
ExplorEnz3.4.21.5
PRIAM enzyme-specific profiles3.4.21.5
KEGG Ligand Database for Enzyme Nomenclature3.4.21.5
IUBMB Enzyme Nomenclature3.4.21.5
IntEnz3.4.21.5
MEDLINEFind literature relating to 3.4.21.5
MetaCyc3.4.21.5
UniProtKB/Swiss-Prot
P00735, THRB_BOVIN;  P00734, THRB_HUMAN;  P19221, THRB_MOUSE;  
Q19AZ8, THRB_PIG;  Q5R537, THRB_PONAB;  P18292, THRB_RAT;  
P84122, THRB_SALSA;  

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