ENZYME entry: EC 3.4.21.53

Accepted Name
Endopeptidase La.
Alternative Name(s)
ATP-dependent protease La.
ATP-dependent serine proteinase.
Reaction catalysed
Hydrolysis of proteins in presence of ATP
Comment(s)
  • ATP hydrolysis is linked with peptide bond hydrolysis.
  • Vanadate inhibits both reactions.
  • A similar enzyme occurs in animal mitochondria.
  • Belongs to peptidase family S16.
Cross-references
PROSITEPDOC00803
BRENDA3.4.21.53
EC2PDB3.4.21.53
ExplorEnz3.4.21.53
PRIAM enzyme-specific profiles3.4.21.53
KEGG Ligand Database for Enzyme Nomenclature3.4.21.53
IUBMB Enzyme Nomenclature3.4.21.53
IntEnz3.4.21.53
MEDLINEFind literature relating to 3.4.21.53
MetaCyc3.4.21.53
UniProtKB/Swiss-Prot
P37945, LON1_BACSU;  Q6ML73, LON1_BDEBA;  Q59185, LON1_BORBU;  
Q6AS16, LON1_DESPS;  A9B5N1, LON1_HERA2;  P36773, LON1_MYXXA;  
Q3A701, LON1_PELCD;  A9ETZ9, LON1_SORC5;  A0LEE9, LON1_SYNFM;  
Q72KS4, LON1_THET2;  Q31GE9, LON1_THICR;  P42425, LON2_BACSU;  
Q6MGP8, LON2_BDEBA;  O51558, LON2_BORBU;  Q6AK61, LON2_DESPS;  
A9B3R2, LON2_HERA2;  P36774, LON2_MYXXA;  Q3A334, LON2_PELCD;  
A9GBF1, LON2_SORC5;  A0LG61, LON2_SYNFM;  Q72JM6, LON2_THET2;  
Q31FD3, LON2_THICR;  A9GIS9, LON3_SORC5;  A9F8L0, LON4_SORC5;  
B7GXS7, LON_ACIB3;  B3ERM8, LON_AMOA5;  Q2IIK1, LON_ANADE;  
O66605, LON_AQUAE;  Q2NJE3, LON_AYWBP;  P77810, LON_AZOBR;  
A8HYF7, LON_AZOC5;  A0RJ87, LON_BACAH;  B5RL78, LON_BORDL;  
P36772, LON_BRECH;  Q2YPX3, LON_BRUA2;  P0C113, LON_BRUAB;  
Q8YHC6, LON_BRUME;  Q8G0I7, LON_BRUSU;  P57549, LON_BUCAI;  
Q8K988, LON_BUCAP;  Q89A99, LON_BUCBP;  B2TFQ5, LON_BURPP;  
A4XJL4, LON_CALS8;  A7ZEJ3, LON_CAMC1;  O69300, LON_CAMJE;  
B8GX12, LON_CAUCN;  P0CAW0, LON_CAUCR;  A9WGB5, LON_CHLAA;  
B8G736, LON_CHLAD;  Q9PK50, LON_CHLMU;  Q9Z9F4, LON_CHLPN;  
B3QSJ7, LON_CHLT3;  O84348, LON_CHLTR;  Q97FT9, LON_CLOAB;  
A6LSV5, LON_CLOB8;  A9KH99, LON_CLOPH;  B5Y8Q8, LON_COPPD;  
Q11QT1, LON_CYTH3;  Q9RXG4, LON_DEIRA;  B8F9K1, LON_DESAA;  
B8J198, LON_DESDA;  A8ZX50, LON_DESOH;  A4J7L6, LON_DESRM;  
Q72CE6, LON_DESVH;  A5EWF3, LON_DICNV;  B5YFG2, LON_DICT6;  
P0A9M1, LON_ECOL6;  P0A9M0, LON_ECOLI;  B2KCC0, LON_ELUMP;  
P46067, LON_ERWAM;  A7HK39, LON_FERNB;  B0S2N4, LON_FINM2;  
A5FG89, LON_FLAJ1;  Q0RPW3, LON_FRAAA;  B0TZA7, LON_FRAP2;  
Q8RHK0, LON_FUSNN;  B5EDX8, LON_GEOBB;  B3E7K2, LON_GEOLS;  
Q39QP7, LON_GEOMG;  P43864, LON_HAEIN;  B8CY71, LON_HALOH;  
B0TFI9, LON_HELMI;  Q9ZJL3, LON_HELPJ;  P55995, LON_HELPY;  
Q1IPZ8, LON_KORVE;  Q1MS21, LON_LAWIP;  Q72UP9, LON_LEPIC;  
A0L516, LON_MAGSM;  Q469F5, LON_METBF;  B8EMF2, LON_METSB;  
Q2NEP8, LON_METST;  B3PN08, LON_MYCA5;  A5IYF2, LON_MYCAP;  
P47481, LON_MYCGE;  Q600B5, LON_MYCH2;  Q6KI22, LON_MYCMO;  
Q6MTF4, LON_MYCMS;  Q8EV77, LON_MYCPE;  P78025, LON_MYCPN;  
Q4A696, LON_MYCS5;  O31147, LON_MYCSM;  Q2GE60, LON_NEOSM;  
Q3JBB6, LON_NITOC;  B3CUN9, LON_ORITI;  A6LD45, LON_PARD8;  
Q6ME13, LON_PARUW;  Q180E4, LON_PEPD6;  B4RI01, LON_PHEZH;  
B2RII6, LON_PORG3;  O69177, LON_RHIME;  Q1RID6, LON_RICBR;  
Q92HZ1, LON_RICCN;  Q4ULN0, LON_RICFE;  Q9ZD92, LON_RICPR;  
Q68WS8, LON_RICTY;  A7NM80, LON_ROSCS;  A8M1E8, LON_SALAI;  
Q32JJ5, LON_SHIDS;  Q026Q2, LON_SOLUE;  A8Z5Z0, LON_SULMW;  
B2V6N0, LON_SULSY;  Q2LVS9, LON_SYNAS;  Q0AWF3, LON_SYNWW;  
A8F811, LON_THELT;  O83536, LON_TREPA;  B1GZQ6, LON_UNCTG;  
B1AIY7, LON_UREP2;  P74956, LON_VIBPA;  B3CLB3, LON_WOLPP;  
Q5H432, LON_XANOR;  

View entry in original ENZYME format
View entry in raw text format (no links)

All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.4.21.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.4.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.-.-.-