ENZYME entry: EC 3.4.21.59

Accepted Name
Tryptase.
Alternative Name(s)
Lung tryptase.
Mast cell protease II.
Mast cell tryptase.
Pituitary tryptase.
Skin tryptase.
Reaction catalysed
Preferential cleavage: Arg-|-Xaa, Lys-|-Xaa, but with more restricted specificity than trypsin
Comment(s)
  • Occurs as a tetrameric molecule with high affinity for heparin, in mast cell granules.
  • Not inhibited by alpha-1-proteinase inhibitor of alpha-2- macroglobulin.
  • Belongs to peptidase family S1.
Cross-references
PROSITEPDOC00124
BRENDA3.4.21.59
EC2PDB3.4.21.59
ExplorEnz3.4.21.59
PRIAM enzyme-specific profiles3.4.21.59
KEGG Ligand Database for Enzyme Nomenclature3.4.21.59
IUBMB Enzyme Nomenclature3.4.21.59
IntEnz3.4.21.59
MEDLINEFind literature relating to 3.4.21.59
MetaCyc3.4.21.59
UniProtKB/Swiss-Prot
Q15661, TRYB1_HUMAN;  Q02844, TRYB1_MOUSE;  P27435, TRYB1_RAT;  
P20231, TRYB2_HUMAN;  P21845, TRYB2_MOUSE;  P50343, TRYB2_RAT;  
Q9BZJ3, TRYD_HUMAN;  P15944, TRYT_CANFA;  P50342, TRYT_MERUN;  
Q9N2D1, TRYT_PIG;  Q9XSM2, TRYT_SHEEP;  

View entry in original ENZYME format
View entry in raw text format (no links)

All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.4.21.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.4.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.-.-.-