ID 3.4.21.6 DE coagulation factor Xa. AN prothrombase. AN prothrombinase. AN Stuart factor. AN thrombokinase. CA Selective cleavage of Arg-|-Thr and then Arg-|-Ile bonds in prothrombin CA to form thrombin. CC -!- A blood coagulation factor formed from the proenzyme factor X by CC limited proteolysis. CC -!- Factor X is a glycoprotein composed of a heavy chain and a light CC chain, which are generated from a precursor protein by the excision CC of the tripeptide RKR and held together by one or more disulfide CC bonds. CC -!- The activated factor Xa converts prothrombin to thrombin in the CC presence of factor Va, Ca(2+) and phospholipids. CC -!- Scutelarin (EC 3.4.21.60) has similar specificity, but does not CC require factor Va. CC -!- Belongs to peptidase family S1. DR Q1L659, FA101_PSETE; Q1L658, FA102_PSETE; P00743, FA10_BOVIN ; DR P25155, FA10_CHICK ; P00742, FA10_HUMAN ; O88947, FA10_MOUSE ; DR O19045, FA10_RABIT ; Q63207, FA10_RAT ; Q4QXT9, FA10_TROCA ; DR Q58L95, FAXC_OXYMI ; Q58L96, FAXC_OXYSU ; Q56VR3, FAXC_PSETE ; DR A6MFK7, FAXD1_DEMVE; P82807, FAXD1_NOTSC; A6MFK8, FAXD2_DEMVE; DR Q58L94, FAXD2_NOTSC; B5G6G5, FAXD_CRYNI ; P83370, FAXD_HOPST ; DR P0CY52, FAXD_NOTSN ; Q58L93, FAXD_PSEPO ; P81428, FAXD_TROCA ; //